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THRILLED to share our recent work: "An Atlas of Cells in the Human Tonsil". @humancellatlas #HCA2022GM
Get ready to SMASH that RT and❤️buttons, because a TWEETORIAL is coming!
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Get ready to SMASH that RT and❤️buttons, because a TWEETORIAL is coming!
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Tonsils are model secondary lymphoid organs (SLO), as they are the first line of defense against many pathogens and are easily accessible. Thus, a complete map of these cells is key to understand how adaptive immunity develops, and to map the cell-of-origin of many lymphomas
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In this setting, we were standing on the shoulders of GIANTS. @hamish_king @louisakjames @WJGreenleaf and colleagues published in 2021 two seminal papers describing the gene expression and open chromatin dynamics during B cell activation at unprecedented resolution.
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