Discover and read the best of Twitter Threads about #HRMM
Most recents (1)
Trying something new today - a thread on high-risk #multiplemyeloma.
I’ll focus this thread on clinical factors and will try to dive into cytogenetics/molecular biology at a later time.
This is my first "tweetorial", so any input/advice/commentary is welcome! #mmsm
1/15
I’ll focus this thread on clinical factors and will try to dive into cytogenetics/molecular biology at a later time.
This is my first "tweetorial", so any input/advice/commentary is welcome! #mmsm
1/15
2/ How is high-risk #myeloma (HRMM) defined and why does it matter?
Most pts with #HRMM respond well to initial tx, but it is often challenging to maintain disease control. Once PD occurs, HRMM is very difficult to treat.
This has potentially important management implications.
Most pts with #HRMM respond well to initial tx, but it is often challenging to maintain disease control. Once PD occurs, HRMM is very difficult to treat.
This has potentially important management implications.
3/ The most widely used tool for risk stratification in MM today is the Revised International Staging System (R-ISS) tinyurl.com/yxjzpk5p. Pts are stratified into one of 3 “stages” based on 4 factors:
1. Albumin
2. Beta-2-microglobulin (B2M)
3. LDH
4. Cytogenetics
1. Albumin
2. Beta-2-microglobulin (B2M)
3. LDH
4. Cytogenetics
