Discover and read the best of Twitter Threads about #HSCT
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5 years ago today I was given a 2nd chance at life. I was diagnosed with diffuse scleroderma and was given 2-5 years to live. After having chemo to eradicate my immune system, I was given my own stem cells back. This saved my life by resetting my immune system.
Today I celebrate!
Today I celebrate!
This was the harvesting process of my stem cells so I wouldn't have any transplant rejection issues.
I had to inject myself with neupogen to produce the stem cells that I needed.
#HSCT
#StemCellTransplant
#NorthWestern
#Chicago
#DrRichardKBurt
#ChemoForTheCure
#AutoImmuneDisease
I had to inject myself with neupogen to produce the stem cells that I needed.
#HSCT
#StemCellTransplant
#NorthWestern
#Chicago
#DrRichardKBurt
#ChemoForTheCure
#AutoImmuneDisease
62 y/o man, O positive with de novo AML undergoes workup for Hematopoietic Stem Cell Transplant (HSCT). 😃Good news: Sibling with 8/8 HLA match! 👎🏽Bad news: Sibling is A positive. Can this sibling be a donor?
#Blooducation #PathTweetorial #HSCT
#Blooducation #PathTweetorial #HSCT
Unlike solid organ transplants, ABO-mismatch HSCT is not a barrier. In fact, 25-50% of all HSCT are ABO-incompatible. The most important factor in transplant survival outcomes is HLA compatibility (Chrom. 6p)
✅Critical to engraftment
✅ Balances potential harm of GVHD vs GVL
✅Critical to engraftment
✅ Balances potential harm of GVHD vs GVL
ABO carbohydrate glycosyltransferases are genes located on chromosome 9 and inherited completed independent of HLA. ABO Ags are not only on RBC membranes, but are also expressed on PLTs, vascular and organ endothelium as well as present in the plasma.
#Blooducation
#Blooducation
