Discover and read the best of Twitter Threads about #Histoplasmosis
Most recents (3)
immune reconstitution inflammatory syndrome #IRIS exaggerated atypical inflammatory response following initiation of ART either paradoxical worsening or unmasking of a infection
#IRIS memory T cells are redistributed from lymphoid tissue to organs, and the number of CD4+ and CD8+ T cells increases faster than that of regulatory T cells, resulting in an imbalance in the immune system
#Histoplasmosis-associated #IRIS rare with an estimated incidence rate of 0.74 cases per 1000 HIV-infected person-years and may present months after initiation of ART
70M with swollen R 5th digit, hand and forearm. No fever / chills.
MRI: complex multi-compartment fluid collection with extensive flexor and extensor tenosynovitis
Debridement. Culture (photo).
What is your diagnosis and Rx?
#MayoIDQ MCQ to follow...
MRI: complex multi-compartment fluid collection with extensive flexor and extensor tenosynovitis
Debridement. Culture (photo).
What is your diagnosis and Rx?
#MayoIDQ MCQ to follow...
Elderly man with swollen right hand and forearm. MRI: complex fluid collection, extensive tenosynovitis. Debridement performed. Culture is shown (photo prior tweet).
Which of the following is the exposure associated with this infection?
Which of the following is the exposure associated with this infection?
3/
Beaver dam and blastomyces
When #IDBR says #beaverdam - you think #BLASTOMYCOSIS
nejm.org/doi/10.1056/NE…
Beaver dam and blastomyces
When #IDBR says #beaverdam - you think #BLASTOMYCOSIS
nejm.org/doi/10.1056/NE…
1/
What happens after you inhale Histoplasma into your lungs? Is #histoplasmosis always a deadly disease?
Here’s a #tweetorial or #pathtweetorial
You are at risk if you live in the Ohio or Mississippi River valleys, go spelunking, or work with chicken coops
What happens after you inhale Histoplasma into your lungs? Is #histoplasmosis always a deadly disease?
Here’s a #tweetorial or #pathtweetorial
You are at risk if you live in the Ohio or Mississippi River valleys, go spelunking, or work with chicken coops
2/
Many (maybe most) people who inhale Histoplasma remain asymptomatic. Many have symptoms that mimic “the flu” and are treated as such. Only a minority of immunocompetent folks are seriously and acutely ill at first exposure. This is called acute pulmonary histoplasmosis.
Many (maybe most) people who inhale Histoplasma remain asymptomatic. Many have symptoms that mimic “the flu” and are treated as such. Only a minority of immunocompetent folks are seriously and acutely ill at first exposure. This is called acute pulmonary histoplasmosis.
3/
What do you think happens next in the vast majority of infected individuals?
What do you think happens next in the vast majority of infected individuals?
