Discover and read the best of Twitter Threads about #ICAD

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Watch here TOMORROW for a new accredited, #tweetorial by neurointensivist @stephanamayer on optimizing DAPT and other interventions for secondary stroke prevention after #AIS or #TIA. Earn 0.5 CE/#CME credits: #physicians, #nurses, #pharmacists! #NoMercyOnStroke @svinsociety
1) Welcome to a #tweetorial on how to optimize therapy for secondary #stroke prevention. Accredited for 0.50 credits! I am your host @stephanamayer. Be sure to see prior tweetorials in the broader cardiometabolic space and earn more CE/#CME credit at cardiometabolic-ce.com Image
Read 54 tweets
#WeekendLecture
Intracranial Atherosclerotic Disease #ICAD

#ICAD leads to changes ranging from minor wall thickening to #hemodynamically significant luminal stenosis and is one of the most #common causes of #stroke worldwide
ahajournals.org/doi/10.1161/CI…

🧵 Image
#WeekendLecture
#ICAD

✅10% of stroke, based on autopsy studies
bit.ly/3v6Lhrd
✅More prevalent in #African Americans, #Hispanics, and #Asians as compared with whites
bit.ly/3AuSiDt

Other risk factors in table Image
#WeekendLecture
#ICAD

In postmortem studies
👉degree of luminal #stenosis
👉% of the plaques containing >40% #lipid area
👉prevalence of intraplaque #hemorrhage, #neovasculature and #thrombus,
were higher in those #plaques associated with #infarct
🔹karger.com/Article/Abstra… Image
Read 13 tweets
#ICAD Tweetorial: Intracranial atherosclerotic disease is the most common cause of stroke worldwide accounting for nearly 10% of ischemic strokes in the United States and up to 50% of ischemic strokes in China.
SAMMPRIS showed that the risk of recurrent events in medically treated ICAD patients was 6.6% at 3 months and 12.2% at 1 year but post-SAMMPRIS studies using real world data demonstrated a rate as high as 25% at 90-days (Stroke. 2017 Aug; 48(8): 2158–2163) @ShyamSprabhak
In #ICAD, rupture of intracraial atherosclerotic plaque leads to thrombus formation. Smaller thrombi can therefore break loose and embolize distally causing distal infarcts. Also, the unstable plaque can extend to occlude perforating branches leading to deep perforator infarcts.
Read 15 tweets

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