Discover and read the best of Twitter Threads about #IDWeek2020

Most recents (17)

#IDWeek2020
Session: Cutting edge adult&ped #TxID

First up, @BrianFisher95 on adenovirus and EBV
#IDWeek2020
Session: Cutting edge adult&ped #TxID
@BrianFisher95

Adenovirus reactivation is more common in pediatric HCT pts, so age is significant risk factor

Chart with reactivation rates, mostly ped data 👇 Progression to sx dz in peds is not uncommon
#IDWeek2020
Session: Cutting edge adult&ped #TxID
@BrianFisher95

So what to do when adenovirus is positive
Read 34 tweets
#IDWeek2020
Session: Viral infections in Ped SOT
Starting with Sharon Chen
#IDWeek2020
Session: Viral infections in Ped SOT
Sharon Chen

1) Thinking about CMV through a new lens
#IDWeek2020
Session: Viral infections in Ped SOT
Sharon Chen

2) Grateful for the discussion on EBV+PTLD one of my interests, we have so so much to learn about this relationship in both adults and pediatrics
Read 19 tweets
#IDWeek2020
So excited for challenging cases in #TxID !

Pearlie Chong @PergamIC @ShohamTxID @nikkitheomd @IDdoc4kids Kate Mullane
#IDWeek2020
Session: Challenging Cases in #TxID
56 yo post-auto HSCT with fever, wt loss, scleral icterus. Labs with low WBC, anemia, elevated LFTs. Not neutropenic.

Check out the smear!
#IDWeek2020
Session: Challenging Cases in #TxID

Dx: Babesiosis - Familiar to us here in MA, but this case was from WA!

Very tough to manage in immunosuppressed pts, require prolonged courses
Read 19 tweets
#IDWeek2020
Session: OPAT in PWID
@mmPharmD

Thinking about how PWID can be treated with OPAT at home
#IDWeek2020
Session: OPAT in PWID
@mmPharmD

OPAT completion in PWID was comparable to those who do not inject drugs

Retrospective studies of carefully selected pts -- but that is also true of who you select in real life
#IDWeek2020
Session: OPAT in PWID
@mmPharmD

No difference in keeping of appts, infusion location, infection type

Longer period of abstinence may indicate better OPAT outcome
Read 13 tweets
#IDWeek2020
Session: Hospital infection control and environmental sustainability: challenges and opportunities!
@preets579

Infection prevention reality vs environmental sustainability - can we achieve a balance?
#IDWeek2020
Session: Hospital IC: challenges and opportunities!
@preets579

Learned about life cycle assessments today!

Reusable gowns had 28% reduction in energy consumption, but data is variable - as in those that did note advantage to reusable laryngoscopes vs single use
#IDWeek2020
Session: Hospital IC: challenges and opportunities!
@preets579

Manufacturers are incentivized to make single use products based on recommendations -- so what is the opportunity here? Does the frame of emerging pathogens shape our ethos towards single use devices?
Read 6 tweets
#IDWeek2020
Session: Challenging Cases #PedsID

Some case thinking in a "COVID-free zone"
#IDWeek2020
Session: Challenging Cases #PedsID

Cerebral toxoplasmosis in alloHCT pt

CSF cytology actually noted tachyzoites - great image!
#IDWeek2020
Session: Challenging Cases #PedsID

Fusobacterium necrophorum causing liver and renal abscess

Anonymous vampire pic appreciated 🧛
Read 7 tweets
Next up, the “What’s Hot in Antifungals?” session by the ever-insightful @DavidAndes, @IDPharmacist, and Dr. Sharon Chen. There’s a lot of development in the antifungal sphere so strap in! @MSG_ERC @GermHunterMD @FungalDoc @GRThompson @IDSA @SIDPharm 1/
So what are the current gaps in available antifungals? Notable gaps include parenteral only, PK distribution to sanctuary sites/urine, toxicity, DDIs, and MDR pathogens (I’m looking at you, the fungus formerly known as S. prolificans). 2/
The novel antifungal pipeline in all of its glory, broken down into similar MOA with improvement in features vs. novel targets/mechanisms.

Some great reviews of newer agents for interested parties:
doi.org/10.1093/ofid/o…
doi.org/10.3390/jof601…
doi.org/10.3390/jof204…
3/
Read 35 tweets
Will be starting soon the ONDEMAND don’t miss this great symposium #LATAM #IDweek2020
Arrancamos, starting with @cla_cor discussing the Changing Face of #HIV in #LATAM & #Caribbean #IDWeek2020
@cla_cor puts up a worrisome statistic #HIV is up 21% in #LATAM #IDweek2020
Read 21 tweets
Dr @HouptEric started the session on Hot Topics in #TB with an overview of #diagnostics and where we are headed #IDWeek2020 @UVA_ID @Tacats99
Our second speaker is DrCaitlin Reed starts us with a case of MDR TB with definitions and how to build a regimen #IDWeek2020
Discussing the recommendations from current @IDSAInfo guidelines idsociety.org/practice-guide… #IDWeek2020 and more clinical trials to shorten the duration 😱😱#TB
Read 5 tweets
Just finished watching the fantastic #IDWeek2020 session “Top Papers in Medical Mycology” by Drs. Jeniel Nett and @petergpappas, highly recommend watching. They covered notable papers, and I took a stab at high-level summaries with screenshots below. @MSG_ERC @IDSAInfo @SIDPharm
1) 10.1371/journal.ppat.1007460 – NDV-3A Vaccine protects mice against MDR-C. auris infection; N-terminus of Als3 protein (major adhesion/invasin from C. alb) formulated with alum; Anti-Als3 Abs in mice recognized C. auris in vitro, blocked biofilm/enhanced macrophage killing. Image
2) 10.1093/cid/ciaa016 – CSF early fungicidal activity as surrogate endpoint for Crypto mening. survival in trials. 738 pts w/ CM & serial LPs; EFA (pic1) measured thru d10 and pts with low EFA had sig. higher 18-wk mortality compared to higher EFA, also low EFA pts ~ low CD4s. ImageImage
Read 15 tweets
#IDWeek2020
Now to watch Mano a Mano, always a great session!! @PIDSociety
#IDWeek2020 #PedsID
Session: Mano a Mano
Should we tx + tracheal cultures?

Con: @asicksamuels
3 Reasons not to treat:
1. Positive cxs do not equal infection
2. Trach cxs are unreliable
3. Treated positive trach cxs do not equal improved outcomes
+
Risk patient harm from over-tx
#IDWeek2020 #PedsID
Session: Mano a Mano
Should we tx + tracheal cultures?

Pro:
VAT assoc'd w/⬆️duration of mech vent, ICU LOS, mortality
Tx of VAT can prevent progression to VAP and perhaps mortality
Treating VAT w/impaired oxygenation is really tx'ing VAP, which is warranted
Read 10 tweets
#IDWeek2020
Session: Shattering the Glass Ceiling

@DrJeanneM

Know your roots and embrace your passions

Don't let someone tell you that you cannot do something, study something because it doesn't fit the mold

But not everyone gets the same encouragement ImageImage
#IDWeek2020
Session: Shattering the Glass Ceiling

@DrJeanneM

So how can we do this concretely? Image
#IDWeek2020
Session: Shattering the Glass Ceiling

@DrJeanneM

You can't do it on your own

Know how to course-correct yourself Image
Read 6 tweets
#IDWeek2020
Session: Shattering the Glass Ceiling

@DrJRMarcelin
Starting from a place a gratitude! Something I should use too! @gradydoctor Image
#IDWeek2020
Session: Shattering the Glass Ceiling

@DrJRMarcelin
Under-representation starts from way before UME/GME and encompasses more than just race, such as LGBQT and disability ImageImage
#IDWeek2020
Session: Shattering the Glass Ceiling

@DrJRMarcelin

There is both a pipeline entry and leak issue in under-representation Image
Read 12 tweets
#IDWeek2020
Session: Shattering the Glass Ceiling

@EmilyBlumbergMD discussing her story and how impactful sponsorship was to her advancement (especially from men) Image
#IDWeek2020
Session: Shattering the Glass Ceiling

@EmilyBlumbergMD Sponsorship is often more difficult for early career women in medicine Image
#IDWeek2020
Session: Shattering the Glass Ceiling

@EmilyBlumbergMD The difference between sponsorship and mentorship!

Sponsorship is more public, and often scarier Image
Read 8 tweets
High yield talk by Pablo Sanchez at #IDWeek2020 session Antimicrobial Stewardship in Pediatric ICUs excellent bundle for #NICU #antibioticstewardship @eerogersmd @PfaffMd excellent work highlighted by @InfectiousNeo @PedsPharmD
Great summary of the harms of broad spectrum antibiotics in #NICU - greeter risk with cephalosporin > aminoglycoside-based therapy
Each additional day adds risk and combined with what we know from @PedsPharmD oral abstract on Global PPS there is a lot of variability in duration - big opportunity to standardize & shorten
Read 4 tweets
Listening to #Africa experience showing how effectively each region responding #chasingthesun #IDWeek2020
What is Africa strategy to plan for development & access of #COVID19 #vaccine? They summarized their approach #chasingthesun #IDWeek2020
#SouthAfrica experience & what work by implementing STRONG public health deliver by @rjlessells #chasingthesun #IDWeek2020
Read 6 tweets
We have listen to Dr Gustavo Lopardo @APInfectologia & Dr @DoctorOmarSued presidente @SADI_ORG Now DrClovis presi @sbinfecto taljing abour silent hypoxemia #IDWeek2020 #chasingthesun u can follow facebook.com/IDWeek/videos/…
Dr @cla_cor Vice President of @SochinfOficial presenting the Good of this #COvId pandemic #chasingthesun #IDWeek2020
Sorry wont be able to post the rest of the talks multitasking can be difficult
Read 7 tweets

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