Discover and read the best of Twitter Threads about #IPFCellAtlas
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1/n The #IPFCellAtlas is finally out! We profiled 312,928 cells from 32 IPF, 28 controls, 18 COPD lungs using @10xGenomics #scRNAseq & identified previously unidentified populations of epithelial & endothelial cells enriched in IPF #CureIPF advances.sciencemag.org/content/6/28/e… 
2/n Among epithelial cells, we identified cells DISTINCT from ANY epithelial cells previously described in human lungs. These aberrant basaloid cells are at the edge of myofibroblast foci & express fibrotic molecules & regulators #IPFCellAtlas #CureIPF advances.sciencemag.org/content/6/28/e…
3/n Among enodthelial cells we discovered a previously undescribed population of COL15A1+ CD31+ cells. They are usually restricted to the airway but in IPF are found in the lung parenchyma - what are they doing there? #IPFCellAtlas #scRNAseq #CureIPF advances.sciencemag.org/content/6/28/e…
