Discover and read the best of Twitter Threads about #ImmuneComplexes

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1/ We detected B. burgdorferi–specific immune complexes containing antibody to unique proteins, including recombinant OspA, and the corresponding antigen.”

What does this mean? Keep reading…
#LymeDisease
2/ It is well known that standard serologic tests for #LymeDisease produce a high rate of false negative results, meaning patients are told they don’t have #Lyme when they really do. As a result, alternate test methods have been developed…but rarely used beyond a research lab.
3/ In the early 1990s, Schutzer & Coyle developed a test that could help diagnose otherwise “seronegative” #LymeDisease cases. They found that antibodies that are bound in “complexes” can cause these false-negative tests.
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