Discover and read the best of Twitter Threads about #Immunosuppressive
Most recents (4)
#Immunosuppressive therapy in virus-negative inflammatory CMP : 20-year follow-up of the #TIMIC trial
Immunosuppressive Tx of virus-negative inflammatory #CMP is associated to a persistent improvement of LV
function and better outcomes during long-term follow-up
#HeartFailure
Immunosuppressive Tx of virus-negative inflammatory #CMP is associated to a persistent improvement of LV
function and better outcomes during long-term follow-up
#HeartFailure
#Immunosuppressive Tx promoted an improvement in cardiac function in 88% of the cases compared the placebo group
A persistent ⤴️ in the #LVEF is seen in long -term (up to 20 years) clinical outcomes of the whole cohort of 85 patients originally enrolled in the #TIMIC trial
A persistent ⤴️ in the #LVEF is seen in long -term (up to 20 years) clinical outcomes of the whole cohort of 85 patients originally enrolled in the #TIMIC trial
Recurring virus-negative myocarditis responding to #immunosuppressive therapy
EKG showing LBBB (A) resolving after therapy (B)
(C and D) Echo apical view showing recovery of LV dysfunction from EF -28% ➡️ up to 51%
#HeartFailure #EchoFirst @ESC_Journals academic.oup.com/eurheartj/adva…
EKG showing LBBB (A) resolving after therapy (B)
(C and D) Echo apical view showing recovery of LV dysfunction from EF -28% ➡️ up to 51%
#HeartFailure #EchoFirst @ESC_Journals academic.oup.com/eurheartj/adva…
Join us tomorrow for the launch of a new accredited tweetorial – a case-based program on the assessment and management of patients with IgA #nephropathy (#IgAN). Free CE/#CME for #physicians, #nurses, #pharmacists! Expert author none other than @IgAN_JBarratt. FOLLOW US . . .
. . . and tell your colleagues to join you here on @ckd_ce, your ONLY source for accredited #tweetorials in the #CKD space! #nephtwitter #nephjc @nephondemand @Nephro_Sparks @edgarvlermamd @ChristosArgyrop @goKDIGO @nicklimd @CKJsocial @ERAkidney @kidney_boy @kidneypathology
1) Welcome to our accredited #tweetorial on optimal contemporary mgt of #IgAN. Earn 0.5h CME/CE credit #physicians #nurses #nursepractitioners #physicianassistants by following this thread. I am @IgAN_JBarratt. @MedTweetorials #nephtwitter #nephjc #FOAMed #MedEd
(1/3) Amazing case study in the American Journal of #Transplantation:
A kidney #transplant patient was being treated for metastatic cancer using a checkpoint inhibitor, which caused the patient's immune system to reject the kidney (...)
onlinelibrary.wiley.com/doi/abs/10.111…
A kidney #transplant patient was being treated for metastatic cancer using a checkpoint inhibitor, which caused the patient's immune system to reject the kidney (...)
onlinelibrary.wiley.com/doi/abs/10.111…
(2/3) After experiencing a complete response, the patient was re-transplanted with a second kidney. This second graft was monitored for rejection using a novel #liquid #biopsy.
This is the first time, to my knowledge, a patient beat cancer and active organ rejection.
This is the first time, to my knowledge, a patient beat cancer and active organ rejection.
(3/3) We think liquid biopsies will fundamentally change the transplant space, allowing doctors to precisely dial #immunosuppressive medication, anticipate organ rejection, and monitor organ health, using a non-invasive approach.
Important paper 👉 They identified several #microbiota components strongly associated w/ white blood cell dynamics☝️Supports the growing reality that we must study the human #immune response in concert w/ the increasing # of #organisms capable of persisting in humans
They also clarify that the #radiation + #chemotherapy administed to hematopoietic cell therapy (HCT) patients can cause loss of #microbiome diversity + commensal microbial families 👉 but microbiome diversity can recover during white blood cell reconstitution
That supports a 2nd important trend 👉 #Immunosuppressive treatments can negatively impact microbiome “health”, while supporting the immune response may have the opposite effect (improved #microbiome dynamics)
