Discover and read the best of Twitter Threads about #InflammAging

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📣 #THREAD: COVID-19 could be a double whammy for older people -- they're more likely to die from it and they might be less likely to respond to a vaccine. This might be due to "#immunosenescence" and "#inflammaging", as I describe in my latest story: nationalgeographic.com/science/2020/0…
Surprise! If you are reading this tweet and past puberty, your thymus gland -- which harbors the T cells that help train the body to make protective antibodies against new viruses (and respond to vaccines) -- is already shrinking: nationalgeographic.com/science/2020/0…
Almost a century ago, Edith Boyd helped confirm that the thymus shrinks with age. Boyd was an anatomist who combed through data from 10,000 autopsies collected at the University of Minnesota and compared them to similar findings from European scientists: nationalgeographic.com/science/2020/0…
Read 12 tweets
#InflammAging (chronic inflammation) may be the main force driving aging & #Omega3 derived Specialized pro-resolving mediators (#SPMs) have many potential #AntiAging benefits via resolution of inflammation/immunomodulation.
sciencedirect.com/science/articl…
nature.com/articles/s4157…
Systemic cytokines/#NFkB is responsible for aging in skeletal stem/progenitor cells (#SSPC's) but new research shows this aging can be reversed by modulating/decreasing these inflammatory factors
(likely most sustainably with high-dose #Omega3). pnas.org/content/116/14… #AntiAging
Is aging a "self-reinforcing loop" of increased systemic inflammation & oxidative stress already increasing at "middle age"? More & more evidence suggest that it is. #Omega3 may decrease both & be a powerful tool to break this vicious loop. nature.com/articles/s4159… #AntiAging
Read 4 tweets

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