Discover and read the best of Twitter Threads about #LC21

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Super excited to finally share this pre-print of our work demonstrating <30 minute sequencing-based somatic variant calls using @nanopore sequencers!

We had a need for speed. A (long) thread... 1/
Why focus on speed? Intraoperative sequencing. Being able to quickly (<1hr) identify actionable mutations *during surgery* has a host of amazing potential use-cases. Imagine generating a personalized molecular diagnostic during biopsy… 2/
...combining biopsy/resection surgeries in real-time, confirming indeterminate frozen section results, intra-operative clinical trial enrollment to test targeted therapies, molecularly targeted chemo delivery directly into resection cavities. The list goes on… 3/
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