Discover and read the best of Twitter Threads about #LymeArthritis

Most recents (3)

Here’s how #LymeDisease testing is rigged.

1. Allen #Steere discovered a genetic association between strong immune response & arthritis.

2. Only about 15% of people fit that profile

Continued…
3. SmithKline needed to *not* diagnose #LymeDisease for their #LYMErix #vaccine trials

4. So they convinced the feds to rig the disease definition so a case of #Lyme = #LymeArthritis ONLY

Continued…
5. This is why #LymeDisease diagnostics are like antibody bingo—rigged to ID only the highly reactive arthritis-prone cases which represent a small minority

6. #LYMErix looked super effective in phase III because the tests would never DX more than 15% of cases!

Continued…
Read 8 tweets
There is a lot of confusion about what #LymeDisease tests under the #CDC #twotier standard are actually designed to diagnose. I’d like to elucidate for all but am feeling kinda lazy, lol. Let’s see here. 1/x
Some think #lymeDisease diagnostics are geared toward #earlylyme only, while some say #latelyme or #LymeArthritis. It’s more specific than that & there is a reliance on timing & interpretation of results to exclude as many cases as possible. 2/x
First of all, one must understand that #LymeDisease & diagnostic test outcomes vary based on people’s genetic makeup, among other factors. People with certain HLAs (studied in-depth by #AllenSteere) tend to have a stronger immune response. 3/x
Read 13 tweets
Let’s discuss #LymeDisease #vaccines.

The topic is getting a lot of play lately, and I’m seeing people who have been socially programmed to hate “antivaxxers” jumping on the “antivaxxers killed the Lyme vaccines” propaganda short bus.

🧵
First of all, the #Lyme vaccines killed themselves. Let’s just be clear on that, once and for all. OspA in any form is not a vaccine. It is one of many lipoproteins expressed on the surface of Borrelia, the organisms that cause #LymeDisease. #LYMErix was recombinant OspA.
You can’t inject these lipoproteins… because…why would you do that when the ticks are perfectly capable??? 🤦‍♀️
Read 33 tweets

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