Discover and read the best of Twitter Threads about #MassSpectrometry
Most recents (2)
1/ How do proteins take their shape in the cell? Insights from our article with @JackJKelly @TheYueLab @UniofOxford @v_paavilainen @HiLIFE_Helsinki @LHapponen @lunduniversity @structbiolbxl @imperialcollege @pfizer nature.com/articles/s4159… #OpenAccess 🧵👇 
2/ #AlphaFold can predict the folded protein shape, but not the complicated folding process itself. Often cells use protein complexes called chaperonins to help other proteins to fold. Here we purified a chaperonin called TRiC from cultured human cells.
3/ Purification was possible only by using #CRISPR genetic scissors. We introduced a purification handle in one of the 8 TRiC subunits. This allowed purification of the endogenous chaperonin as opposed to an engineered version of it. Quite a TRiCK! #samplerevolution
It's good to be back! Follow this thread for the video stream & live coverage of tonight's first SFI Community Lecture at @TheLensic in two years, featuring @Sara_Imari on the #physics of living #systems.
And stay tuned for an extraordinary lineup of additional talks this year...
And stay tuned for an extraordinary lineup of additional talks this year...
Live stream starts in one minute!
SFI's @ChrisKempes introduces tonight's speaker @Sara_Imari (@sfiscience, @beyond_asu) by quoting #HaroldMorowitz about how, to find life beyond Earth, we must understand the *origins* of life...
