Discover and read the best of Twitter Threads about #MassSpectrometry

Most recents (2)

1/ How do proteins take their shape in the cell? Insights from our article with @JackJKelly @TheYueLab @UniofOxford @v_paavilainen @HiLIFE_Helsinki @LHapponen @lunduniversity @structbiolbxl @imperialcollege @pfizer nature.com/articles/s4159โ€ฆ #OpenAccess ๐Ÿงต๐Ÿ‘‡
2/ #AlphaFold can predict the folded protein shape, but not the complicated folding process itself. Often cells use protein complexes called chaperonins to help other proteins to fold. Here we purified a chaperonin called TRiC from cultured human cells.
3/ Purification was possible only by using #CRISPR genetic scissors. We introduced a purification handle in one of the 8 TRiC subunits. This allowed purification of the endogenous chaperonin as opposed to an engineered version of it. Quite a TRiCK! #samplerevolution
Read 8 tweets
It's good to be back! Follow this thread for the video stream & live coverage of tonight's first SFI Community Lecture at @TheLensic in two years, featuring @Sara_Imari on the #physics of living #systems.
And stay tuned for an extraordinary lineup of additional talks this year...
Live stream starts in one minute!
SFI's @ChrisKempes introduces tonight's speaker @Sara_Imari (@sfiscience, @beyond_asu) by quoting #HaroldMorowitz about how, to find life beyond Earth, we must understand the *origins* of life...
Read 28 tweets

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