Discover and read the best of Twitter Threads about #MechanismsOfAging

Most recents (1)

Cool #Senescence paper #2, in @JCI_insight: insight.jci.org/articles/view/….

@marissa_schafer, Xu Zhang, @NKLeBRASSEUR & team dive into the details of SASP, the Senescence Associated Secretory Phenotype first discovered in the Campisi lab @BuckInstitute.
SASP is a prime suspect for how #Senescent cells cause #Inflammation, #Cancer and #Fibrosis. But SASP is a mix of many secreted proteins, so the @MayoClinic looked closely at 24 factors.
1st, they show which factors are secreted by different cell types (in culture).
Next, and more exciting, they measured which SASP factors increase with age in human blood. #ChronicInflammation is an important mechanism of aging, but really defining #ChronicInflammation is hard and often not even attempted. So this detailed analysis is great.
Read 4 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!