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2 brothers in their 30’s presented to us with progressive Cerebellar ataxia. On examination, there is slightly restricted vertical gaze.
Thoughts ?
#MedTwiter #NeuroTwitter #Neurology
Thoughts ?
#MedTwiter #NeuroTwitter #Neurology
One of the typical features of Niemann-Pick C disease is SUPRANUCLEAR VERTICAL GAZE PALSY
Ataxia, Dystonia Psychomotor Regression are common
GELASTIC CATAPLEXY is another common feature
Ataxia, Dystonia Psychomotor Regression are common
GELASTIC CATAPLEXY is another common feature
The disease follows an Autosomal Recessive inheritance and unlike A/B, C can present in older ages with neurological features, without hepatosplenomegaly
#mmsm Hematologica published 3 articles for sub-group analysis for Isatuximab recently:
1-IKEMA pts with renal failure-Full article
2- ICARIA-MM elderly pt-letter to editor
3-IKEMA+ICARIA-MM: 1q-letter to editor
🛑All used 1-2 medical writers
Was this all the story ? 🧵
1-IKEMA pts with renal failure-Full article
2- ICARIA-MM elderly pt-letter to editor
3-IKEMA+ICARIA-MM: 1q-letter to editor
🛑All used 1-2 medical writers
Was this all the story ? 🧵
Same medical writers helped in a review of key subgroup analysis of ICARIA-MM 👇
Also in doing another subgroup analysis in high risk cytogenetics
Also in doing another subgroup analysis in high risk cytogenetics
You think we are done: NO
ICARIA-MM subgroup analysis 👇
Expert review article with the help of medical writer 👇
ICARIA-MM subgroup analysis 👇
Expert review article with the help of medical writer 👇
