Discover and read the best of Twitter Threads about #Mycology
Most recents (15)
Did you know mushrooms can stab through rock?🔪🪨
Fungi's "roots", called hyphae, can bore right through stone and played a significant role in creating soil.
Yup, thats right, mushrooms are older than dirt. They MADE dirt.
IM ABOUT TO TELL YOU ABOUT THESE RAD STABBY BOYS 🧵
Fungi's "roots", called hyphae, can bore right through stone and played a significant role in creating soil.
Yup, thats right, mushrooms are older than dirt. They MADE dirt.
IM ABOUT TO TELL YOU ABOUT THESE RAD STABBY BOYS 🧵
Important context: hyphae are the branching filaments that make up fungi. The mycelium (which is like the "root system") is made of these tiny tendrils, and the mushroom is too, all stacked up! They are long tubular structures, like a hose, but TEENY (4 to 6 microns thick).
1/2 billion years ago, the terrestrial world was mostly just rocks, but then fungi (and other micro-organisms) starting boring into the stone and breaking it up into minerals and eventually soil so that plants could move onto land. BUT THAT'S JUST THE BEGINNING!
A 50-YO♂️of North India, visited bat caves & a bird sanctuary in Thailand: multiple plaques & nodules on his face, neck, arms & trunk with hoarseness, fever, weight loss for months
Laryngoscopy: nodules over the tonsils & posterior pharyngeal wall
1/4
#medicine #dermatology
Laryngoscopy: nodules over the tonsils & posterior pharyngeal wall
1/4
#medicine #dermatology
Skin & laryngeal 🔬: histiocytes with intracellular & extracellular PAS+ yeast cells
Skin biopsy🧫: tuberculate macroconidia confirmed as H. capsulatum var. capsulatum
Ab against Histoplasma by ID:➕
DISSEMINATED HISTOPLASMOSIS
2/4
doi.org/10.3109/136937…
#mycology #IDtwitter
Skin biopsy🧫: tuberculate macroconidia confirmed as H. capsulatum var. capsulatum
Ab against Histoplasma by ID:➕
DISSEMINATED HISTOPLASMOSIS
2/4
doi.org/10.3109/136937…
#mycology #IDtwitter
Disseminated histoplasmosis involving skin & larynx in an apparently immunocompetent individual
The infection appeared to be imported from Thailand.
The patient responded very well to intravenous amphotericin B followed by itraconazole.
3/4
#microbiology #MedTwitter #Doctor
The infection appeared to be imported from Thailand.
The patient responded very well to intravenous amphotericin B followed by itraconazole.
3/4
#microbiology #MedTwitter #Doctor
A 46-YO ♂️: oropharyngeal lesions, cervical lymphadenopathy, intermittent fever, hepatosplenomegaly, and deteriorating general health.
Needle aspiration from submandibular lymph node: intra- and extracellular yeasts
1/4
DOI:
doi.org/10.4269/ajtmh.…
#dermpath #mycology
Needle aspiration from submandibular lymph node: intra- and extracellular yeasts
1/4
DOI:
doi.org/10.4269/ajtmh.…
#dermpath #mycology
The histopathology of oral lesion showed features of HISTOPLASMOSIS confirmed later from culture of Histoplasma capsulatum on culture
2/4
#IDtwitter #microbiology #MedTwitter
2/4
#IDtwitter #microbiology #MedTwitter
In immunocompetent hosts, when chronic disseminated histoplasmosis occurs from pulmonary infection, oral ulcers, nodules, and vegetative plaques are common and dissemination to liver, spleen, bone marrow, and other organs is frequent.
3/4
#Doctor #MedStudentTwitter #resident
3/4
#Doctor #MedStudentTwitter #resident
A 37-YO, farmer in India, #HIV+ immunecompromised ♂️, treatment for suspected pulmonary tuberculosis: papulonodular lesions of 3-month duration over the face, neck, trunk, limbs, palms & soles, & oropharynx; fever & generalized lymphadenopathy
🔬: ?
1/7
#IDTwitter #microbiology
🔬: ?
1/7
#IDTwitter #microbiology
🔬: Blastoconidias within the macrophages.
🧫: Histoplama capsulatum: characteristic colony, conversion to yeast form, characteristic🔬appearance.
PROGRESSIVE DISSEMINATED HISTOPLASMOSIS
2/7
doi: 10.4269/ajtmh.17-0432
#dermpath #mycology #internalmedicine
🧫: Histoplama capsulatum: characteristic colony, conversion to yeast form, characteristic🔬appearance.
PROGRESSIVE DISSEMINATED HISTOPLASMOSIS
2/7
doi: 10.4269/ajtmh.17-0432
#dermpath #mycology #internalmedicine
Diagnosis is usually suspected on visualization of characteristic intracellular yeast (blastoconidias), the pathogenic or tisular form, with a clear rim and garnulomatous cellular infiltrate in tissue specimen or lymph node aspirate
3/7
#MedTwitter #Doctor
3/7
#MedTwitter #Doctor
A 20-YO ♀️, college wrestling, Mexico: itching in the past 2 months, erythematous & fine-scaling papules with annular plaques having a raised border affecting the face, neck, & torso.
1/6
doi: 10.18502/cmm.6.4.5439
#dermatology #primarycare #MedTwitter
1/6
doi: 10.18502/cmm.6.4.5439
#dermatology #primarycare #MedTwitter
KOH: multiple thin & septate hyphae.
🧫, MALDI-TOF-MS: Trichophyton tonsurans
T. tonsurans was isolated in 4 cases belonging to the school fighting team & from one of the training mats
TINEA GLADIATORUM DUE TO TRICHOPHYTON TONSURANS IN A SCHOLL WRESTLING TEAN
2/6
#mycology
🧫, MALDI-TOF-MS: Trichophyton tonsurans
T. tonsurans was isolated in 4 cases belonging to the school fighting team & from one of the training mats
TINEA GLADIATORUM DUE TO TRICHOPHYTON TONSURANS IN A SCHOLL WRESTLING TEAN
2/6
#mycology
Oral terbinafine for 3 weeks: clinical & mycological cure.
Tinea gladiatorum is a type of dermatophytosis that occurs in combat athletes, such as wrestlers and judo fighters, as a result of Trichophyton species.
3/6
doi: 10.18502/cmm.6.4.5439
#IDtwitter #microbiology #Doctor
Tinea gladiatorum is a type of dermatophytosis that occurs in combat athletes, such as wrestlers and judo fighters, as a result of Trichophyton species.
3/6
doi: 10.18502/cmm.6.4.5439
#IDtwitter #microbiology #Doctor
A 4-YO♂️ treated for tuberculosis for 3 years with chronic cough, kyphosis, recurrent pneumonia, rib osteomyelitis: lung consolidation, mediastinal lymphadenopathy, cervical kyphosis; R-sided paravertebral soft tissue swelling (T3 to T6)
1/7
#IDtwitter #radiology #Orthopedics
1/7
#IDtwitter #radiology #Orthopedics
Serology: ➕for Aspergillus flavus & Aspergillus fumigatus.
Aspiration of the paravertebral soft tissue:
🔬granulomatous inflammation
🧫Acinetobacter spp.
VERTEBRAL OSTEOMYELITIS & ACINETOBACTER SPP PARAVERTEBRAL SOFT TISSUE INFECTION
2/7
#microbiology #MedTwitter
Aspiration of the paravertebral soft tissue:
🔬granulomatous inflammation
🧫Acinetobacter spp.
VERTEBRAL OSTEOMYELITIS & ACINETOBACTER SPP PARAVERTEBRAL SOFT TISSUE INFECTION
2/7
#microbiology #MedTwitter
Nitroblue tetrazolium dye reduction test: no reduction of the nitroblue tetrazolium
No right shift noted in the activated neutrophils in flow cytometry-based DHR assay (E, patient; F, control)
CHRONIC GRANULOMATOUS DISEASE
3/7
DOI: 10.1097/INF.0000000000001221
#medicine
No right shift noted in the activated neutrophils in flow cytometry-based DHR assay (E, patient; F, control)
CHRONIC GRANULOMATOUS DISEASE
3/7
DOI: 10.1097/INF.0000000000001221
#medicine
Mucormycosis:
1. Fatal invasive disease with high mortality
2. Genus: rhizopus, mucor, cunninghamella, lichtheimia etc
3. Risk factors: Uncontrolled DM, DKA, neutropenia, prolonged glucocorticoid use, elevated levels of free iron, SOT, HSCT, COVID-19 infection.
1. Fatal invasive disease with high mortality
2. Genus: rhizopus, mucor, cunninghamella, lichtheimia etc
3. Risk factors: Uncontrolled DM, DKA, neutropenia, prolonged glucocorticoid use, elevated levels of free iron, SOT, HSCT, COVID-19 infection.
4. Rhino-orbital-cerebral disease: most common form, seen in diabetes, steroid use. Ethmoid sinus-->orbit-->frontal lobe/cavernous sinus, hard palate in advanced case.
5. Pulmonary disease: second most common, in organ transplant, chemotherapy receiving pt.
5. Pulmonary disease: second most common, in organ transplant, chemotherapy receiving pt.
6. Cutaneous: hematogenous dissemination or direct inoculation. Can be highly invasive. Needs prompt debridement.
7. GIT: GI bleeding, fungating mass seen at UGIE, perforation, high mortality.
8. Disseminated disease: most common site is brain. Mortality >90%.
7. GIT: GI bleeding, fungating mass seen at UGIE, perforation, high mortality.
8. Disseminated disease: most common site is brain. Mortality >90%.
Aspergillosis (disease spectrum, Dx, Rx):
1. Refers collectively to all invasive and allergic disease caused by aspergillus species
2. A.fumigatus: causes most of the invasive & chronic aspergillosis & allergic disease
3. A.flavus: sinus, cutaneous infection & keratitis
1. Refers collectively to all invasive and allergic disease caused by aspergillus species
2. A.fumigatus: causes most of the invasive & chronic aspergillosis & allergic disease
3. A.flavus: sinus, cutaneous infection & keratitis
4. A.niger: otitis externa
5. It's a hyaline, septate branching mold
6. Risk factors: neutropenia, glucocorticoid use, CGD, severe influenza or Covid-19, COPD, pulmonary TB, infliximab, ibrutinib use, ECMO
7. Invasiv: pulmonary, sinusitis, cutaneous, endocarditis, cerebral
5. It's a hyaline, septate branching mold
6. Risk factors: neutropenia, glucocorticoid use, CGD, severe influenza or Covid-19, COPD, pulmonary TB, infliximab, ibrutinib use, ECMO
7. Invasiv: pulmonary, sinusitis, cutaneous, endocarditis, cerebral
8. Chronic pulmonary aspergillosis(CCPA) : single or multiple cavities in upper lobe, a/w fatigue, weight loss, hemoptysis, prior lung disease like TB etc, untreated can cause fibrosis & destroyed lung
9. Aspergilloma: fungal ball. A/w CPA.
9. Aspergilloma: fungal ball. A/w CPA.
A 59-YO DM, steroid, myasthenia gravis with thymoma: headache & deviation of tongue to the R side with fasciculation suggestive of right 12th cranial nerve palsy
CT: sphenoid sclerotic changes, soft tissue density lesion with calcification.
1/9
#neurology #radiology #IDtwitter
CT: sphenoid sclerotic changes, soft tissue density lesion with calcification.
1/9
#neurology #radiology #IDtwitter
MRI brain: a hypointense lesion involving the body of sphenoid (R > L) and clivus on T2 weighted images and T1 weighted images with moderate contrast enhancement possibly fungal in aetiology.
2/9
doi.org/10.1016/j.idcr…
#radiologist #radres #MedTwitter
2/9
doi.org/10.1016/j.idcr…
#radiologist #radres #MedTwitter
Endoscopic sphenoidotomy & debridement: invasive fungal sphenoid sinusitis & CENTRAL SKULL BASE OSTEOMYELITIS involving the clivus
🔬from sphenoid mucosa: morphologically ASPERGILLUS with foci of tissue invasion.
3/9
#microbiology #maxillofacial #Orthopedics
🔬from sphenoid mucosa: morphologically ASPERGILLUS with foci of tissue invasion.
3/9
#microbiology #maxillofacial #Orthopedics
A 63-year old man, kidney transplantation: fever and a painful ulcer on the lateral side of the tongue.
🔬: showed invasion of X?
1/8
doi.org/10.1016/j.idcr…
#OralPath #maxillofacial #nephrology
🔬: showed invasion of X?
1/8
doi.org/10.1016/j.idcr…
#OralPath #maxillofacial #nephrology
🔬 showed invasion of Cryptococcus neoformans.
A tongue swab:➕for HSV-1.
The cryptococcal antigen test on serum: ➕
CRYPTOCOCCOSIS TONGUE ULCER IN A RENAL TRANSPLANT PATIENT
2/8
#mycology #Pathologists #microbiology
A tongue swab:➕for HSV-1.
The cryptococcal antigen test on serum: ➕
CRYPTOCOCCOSIS TONGUE ULCER IN A RENAL TRANSPLANT PATIENT
2/8
#mycology #Pathologists #microbiology
A CT-scan of the lungs showed extensive ground glass lesions & a lesion of 4.7 cm in the left upper lobe.
Bronchoalveolar lavage:➕for Cryptococcus neoformans & Pneumocystis jirovecii.
LUNG COINFECTION OF C. NEOFOMANS & P. JIROVECII
3/8
#IDtwitter #MedTwitter
Bronchoalveolar lavage:➕for Cryptococcus neoformans & Pneumocystis jirovecii.
LUNG COINFECTION OF C. NEOFOMANS & P. JIROVECII
3/8
#IDtwitter #MedTwitter
A 19-YO woman: a 6-month history of a slowly growing, nonscaling, nonpalpable brown patch on the left palm (A).
1/6
DOI: 10.1056/NEJMicm2204411
#dermatology #mycology #MedEd
1/6
DOI: 10.1056/NEJMicm2204411
#dermatology #mycology #MedEd
🔍: curvilinear brown strands — also known as pigmented spicules — that formed a reticular pattern distinct from the palmar furrows (B).
🔬palmar skin scrapings, H&E: pigmented yeast and hyphae (C).
TINEA NIGRA
2/6
#IDtwitter #MedStudentTwitter
🔬palmar skin scrapings, H&E: pigmented yeast and hyphae (C).
TINEA NIGRA
2/6
#IDtwitter #MedStudentTwitter
Tinea nigra is an uncommon superficial mycosis, often grouped with the dermatophytes, but caused by the melanin-producing dimorphic yeast Hortaea werneckii.
3/6
#microbiology #dermatología
3/6
#microbiology #dermatología
👩🦳 in her 70s: on the L 🦶, initially appeared pruritic papules that evolved to fluid-filled blisters with tense and denuded bullae (Fig1).
Over the ensuing 6 weeks an expanding annular plaque with peripheral scale (Fig2).
¼
DOI:doi.org/10.1016/j.mayo…
#dermatology #mycology
Over the ensuing 6 weeks an expanding annular plaque with peripheral scale (Fig2).
¼
DOI:doi.org/10.1016/j.mayo…
#dermatology #mycology
🔬(KOH): hyphae
🧫: Trichophyton rubrum
BULLOUS TINEA PEDIS.
The patient responded well to terbinafine cream and dilute acetic acid soaks.
2/4
#microbiology #IDtwitter
🧫: Trichophyton rubrum
BULLOUS TINEA PEDIS.
The patient responded well to terbinafine cream and dilute acetic acid soaks.
2/4
#microbiology #IDtwitter
Bullous tinea, seen in adults and children, and most often affecting the feet, presents with an erythematous scaly rash with serous fluid-filled bullae, as opposed to the pus-filled blisters of bullous impetigo.
3/4
#MedTwitter #Doctor #MedStudentTwitter #MedEd
3/4
#MedTwitter #Doctor #MedStudentTwitter #MedEd
34-YO👨🦰congenital, idiopathic intestinal pseudo-obstruction, total parenteral nutrition & infusion of lipid emulsions: fever & cough (paroxysmal coughing with his port infusion)
CXR: interstitial infiltrates & areas of faint alveolar opacities
Portacath blood
1/
#microbiology
CXR: interstitial infiltrates & areas of faint alveolar opacities
Portacath blood
1/
#microbiology
Smear: globose, oval, budding #yeast with a small collarette, suggesting Malassezia spp.
Olive oil–supplemented🧫: Malassezia sympodialis (identified by DNA sequencing)
FUNGEMIA INFECTION & LUNG EMBOLI BY MALASSEZIA SYMPODIALIS IN THE PORTACATH VENOUS ACCESS SYSTEM
2/
#MedEd
Olive oil–supplemented🧫: Malassezia sympodialis (identified by DNA sequencing)
FUNGEMIA INFECTION & LUNG EMBOLI BY MALASSEZIA SYMPODIALIS IN THE PORTACATH VENOUS ACCESS SYSTEM
2/
#MedEd
The portacath was removed, & the patient was given liposomal amphotericin B, for 4 weeks.
His symptoms were gone by week 2, and the interstitial infiltrates were nearly resolved by week 4.
3/
doi.org/10.1093/cid/ci…
#mycology #IDtwitter #MedTwitter
His symptoms were gone by week 2, and the interstitial infiltrates were nearly resolved by week 4.
3/
doi.org/10.1093/cid/ci…
#mycology #IDtwitter #MedTwitter
Oyster mushrooms will grow on almost any carbon-rich material. Chances are, you've got all you need to get started tucked away in your recycling bin. ♻️🦪
How to build a cardboard digester a thread:
How to build a cardboard digester a thread:
📦Find/build a crate with some room between the slats for your mushrooms to emerge from. About 1" spaces are good. Milk crates work too!
📜Source enough undyed/brown cardboard and paper to fill the crate. You can also add some freshly used coffee grounds or even a little compost.
📜Source enough undyed/brown cardboard and paper to fill the crate. You can also add some freshly used coffee grounds or even a little compost.
🚿 Hydrate your materials by giving them a hose down or soak in a tub for a few minutes. Let any excess water drain off.
🥪 Inoculate! Sandwich your crumbled oyster sawdust spawn between layers of cardboard and paper.
🥪 Inoculate! Sandwich your crumbled oyster sawdust spawn between layers of cardboard and paper.
Hello! I'm Tapoka (@TapokaM) from
@BlackInMicro SM team. Today is #BlackInMycology and #BlackInParasitology day! #Parasitology is one of my faves. I have a soft spot for nematodes, as I study #Whipworm & I’m incredibly excited to learn about #Mycology over the day! 🍄🪱
@BlackInMicro SM team. Today is #BlackInMycology and #BlackInParasitology day! #Parasitology is one of my faves. I have a soft spot for nematodes, as I study #Whipworm & I’m incredibly excited to learn about #Mycology over the day! 🍄🪱
#ParasitologyInRealLife for me often looks a lot like this, I spend a lot of time with our microscopes. I want to understand how whipworm eggs and the host gut bacteria interact. So I dissect a lot of guts and I look at many eggs 🪱🥚
Here’s a very small wave hello 👋🏾 from the mouse whipworm Trichuris muris 🐛 #ParasitologyInRealLife
