Discover and read the best of Twitter Threads about #NFKB

Most recents (4)

Step 1 - accept chronic illness as present
Step 2 - pursue THOROUGH self-care solutions
Step 3 - Prenatal/Child page is good for the family (no elderly specific info on the page though) jenniferdepew.com/prenatal%2Fchi…
Step 4 - autoimmune & mitochondrial support! docs.google.com/document/d/1Rm…
Step 5 -
"Doctors can't help or they refuse to help. " @BlueSlots
<- accept that that statement, sadly, is factual - the medical system has been taught wrong. They are either confident in their wrong methods, or complicit with the culling. CAUTION entering care & losing rights
Once in a hospital setting the patient and family can have little control over what happens next.

The US CoV death rates STRONGLY suggest that the US CoV "protocols" are quite DEADLY.
Read 20 tweets
New paper out! Our own David Zander has successfully published his thesis work in @cddpress’ Cell Death & Disease!

Just to highlight this: David is an MD but he worked his tail off pipetting this study! A big Thank You to @TRR179_2 for the stipend!

1/6

nature.com/articles/s4141…
So what is it about?
• Damage to our cells’ genome DNA can lead to #cancer if it goes unnoticed (cell not committing suicide).
• Vice versa, many chemotherapies (and radiotherapy!) are based on killing cells by inducing #DNADamage.

In his study, David used…
2/6
…live cell microscopy (@EssenBioScience) to monitor cell proliferation and death upon treatment with doxorubicin (chemotherapeutic inducing DNA breaks) or gamma-irradiation (γIR). As expected, both treatments kill cells ⬇️

3/6
Read 7 tweets
Really chuffed to share our latest work from Sanjana Lab out in @nature today (nature.com/articles/s4158…).

We tested >12,000 genes to find positive regulators of T cell proliferation to be used for next-gen #immunotherapies.

A thread...
(2/28) T cell therapies have shown the potential to cure patients from #cancer – but even in B cell cancers, relapses outnumber cures… One of the problems is limited T cell persistence. #celltherapy #CARTcell
(3/28) We wanted to find new genes (including genes never expressed in T cells) that could improve T cell persistence. Now, the question was: should we use #crispr activation or directly deliver target genes on a #lentivirus?
Read 30 tweets
#InflammAging (chronic inflammation) may be the main force driving aging & #Omega3 derived Specialized pro-resolving mediators (#SPMs) have many potential #AntiAging benefits via resolution of inflammation/immunomodulation.
sciencedirect.com/science/articl…
nature.com/articles/s4157…
Systemic cytokines/#NFkB is responsible for aging in skeletal stem/progenitor cells (#SSPC's) but new research shows this aging can be reversed by modulating/decreasing these inflammatory factors
(likely most sustainably with high-dose #Omega3). pnas.org/content/116/14… #AntiAging
Is aging a "self-reinforcing loop" of increased systemic inflammation & oxidative stress already increasing at "middle age"? More & more evidence suggest that it is. #Omega3 may decrease both & be a powerful tool to break this vicious loop. nature.com/articles/s4159… #AntiAging
Read 4 tweets

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