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Last week, @PharmToTablePod dropped the 1st in a series of episodes dealing with nucleoside chemistry. In this three part series we will walk you thru different types of challenges with these molecules at different stages of drug discovery. #MerckChemistry podcasts.apple.com/us/podcast/pha…
Given that we are dedicating 3 episodes on this topic, I thought it would be good to offer some baseline nucleoside basics for you in case you aren’t familiar with this topic, in this 🧵 I’ll call #Nuceloside101
The relevance of these building blocks in pharma is largely driven by their importance in the biology, particularly RNA and DNA. These nucs vary by the hydroxylation pattern. #Nucleoside101 
