Discover and read the best of Twitter Threads about #OSELTAMIVIR

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THREAD: Evidence for oseltamivir for #influenza prevention

1/6 Not much #flu last year, yet almost 14,000 BC residents were prescribed #oseltamivir (Tamiflu) for prevention

✅Flu guidelines bit.ly/3wwGJei

✅Systematic review of Tamiflu safety pubmed.ncbi.nlm.nih.gov/27246259
2/6 #Oseltamivir for prevention reduces ↘️ symptomatic influenza by 3%, (NNT=33) with an uncertain effect on asymptomatic #influenza

It likely has a central symptom reducing effect but may not reduce viral transmission
pubmed.ncbi.nlm.nih.gov/27246259

#Tamiflu #prescribing
3/6 #Oseltamivir won’t reduce the risk of developing influenza-like illness though it can make people feel better (i.e. fewer symptoms) and reduces ↘️ fever

There is not enough evidence to say it prevents death, hospitalizations, or flu complications
pubmed.ncbi.nlm.nih.gov/27246259
Read 7 tweets
IMPORTANT THREAD on #COVIDTreatments - What Works & What Does not. Will be an ongoing threat.

Start with Dr Zarir Udwadia of Mumbai.
Link to Dr Udwadia's Video


1st Point: 90000+ Medical papers on Covid. UNFORTUNATELY, big divergence in Observational Studies impact and Real World impact of a rigorous RCT
RCT is Randomized controlled trial.
A Good website is Covid19Primer.com

2) What Works ?
(A) Steroids are essential. #DEXAMETHASONE 6mg/day for Critically ill Covid Patients. Reduces Death by 33/20% for Patients on Ventilators & Oxygen. ImageImageImage
Read 19 tweets
MEDICAMENTOS PARA #COVID19

Desde diciembre 2019 que se reportó el primer caso de infección por #SARS_CoV_2, han surgido un sinfín de tratamientos para esta infección.

¿Pero cual tiene suficiente evidencia científica?

Abro hilo
Empecemos por dejar en claro varios puntos:

#COVID19: Enfermedad provocada por la infección #SARSCoV2.

#SARSCoV2: Nuevo tipo de #coronavirus que por sus siglas en inglés se refiere a 𝘴𝘦𝘷𝘦𝘳𝘦 𝘢𝘤𝘶𝘵𝘦 𝘳𝘦𝘴𝘱𝘪𝘳𝘢𝘵𝘰𝘳𝘺 𝘴𝘺𝘯𝘥𝘳𝘰𝘮𝘦 𝘤𝘰𝘳𝘰𝘯𝘢𝘷𝘪𝘳𝘶𝘴 𝟸
Es decir, puedes tener la infección pero no desarrollar la enfermedad.

Esto es importante para entender la clasificación los @NIH para la infección por #SARSCoV2:

1.- Asintomático
2.- Cuadro leve
3.- Cuadro moderado
4.- Cuadro severo
5.- Cuadro criticó

covid19treatmentguidelines.nih.gov/whats-new/
Read 49 tweets
#Remdesivir begins distribution in the #USA today via #EUA.

I thought would write down some practical #tips based on my #qualitative anecdotal experience after personally treating close to 200 patients with #COVID19.

For quantitative results, wait for the papers¬—thread
“this juice works, doc!” When you hear similar expressions 1-2 days after starting #remdesivir multiple times, you start to wonder. Don't recall a similar proportion of patients smile after feeling so sick 1-2 days earlier with #COVID19. x/n? Wait for the papers.
Like #treatment for any severe infectious disease (meningitis, Gram-negative bacteremia, influenza pneumonia, etc), earlier is always better. #COVID19 is no different. #Remdesivir stops #SARS-CoV2 replication, but won’t heal the lung injury.
Read 13 tweets
1) We are going to breakdown what these meds are here.

#Coronavirus #2019nCoV #WuhanCoronvirus

The first one.

头孢地尼胶囊
Cefdinir capsule is an antibiotic used to treat pneumonia, otitis media, strep throat, and cellulitis.
Ref: en.wikipedia.org/wiki/Cefdinir
2) 連花清瘟膠囊
Lianhua Qingwen

They have 2 of these boxes. This is a herbal medicine.
Interestingly studies show it to be more effective for treating flu.

#Coronavirus #2019nCoV #WuhanCoronvirus

ncbi.nlm.nih.gov/pubmed/29071849
3) 磷酸奥司他韦 胶囊
Oseltamivirphosphate

#Oseltamivir, sold under the brand name #Tamiflu, is an antiviral medication used to treat and prevent #influenza A and influenza B (flu).

#Coronavirus #2019nCoV #WuhanCoronvirus

Drug Ref: webmd.com/drugs/2/drug-1…
Read 15 tweets

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