Discover and read the best of Twitter Threads about #OrganonaChip

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WOW!

La FDA (agencia de EE.UU. responsable de la regulación de alimentos, medicamentos, etc.) ya no necesita exigir pruebas en animales antes de los ensayos de medicamentos en humanos.
"Para autorizar medicamentos para ensayos en humanos, la agencia debe confiar más en el modelado #InSilico, los #OrganOnAChip y otros métodos sin animales #NewApproachMethodologies que se han desarrollado en los últimos 10 a 15 años."
"Algunas farmas habían mostrado su enfado con el requisito de la FDA de realizar pruebas con animales, argumentando que estos estudios son muy costosos, lo que ralentiza el desarrollo de fármacos y hace que los medicamentos que llegan al mercado sean mucho más caros."
Read 13 tweets
Over 70% of drugs that seem promising in animal studies fail when tested in humans. Organ-on-a-chip technology could radically change this picture. whatisbiotechnology.org/index.php/scie…
Designed with cells from the human body, as this series of tweets show #Organonachips have taken many decades to materialise, starting with John Syer Bristoe’s idea for an artificial organ in 1876 John_SyerBristowe was a British Physician based at St Thomas
The development of #Organonachip is rooted in the concept of the #3Rs (Reduce, Refine and Replace animal testing) first outlined in 1959 by William Russell and Rex Burch
Read 18 tweets

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