Discover and read the best of Twitter Threads about #PARACHUTETrial

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Have you heard of #PARACHUTETrial?

@rwyeh & his team convinced 23 adventurous people to jump out of a plane wearing either a parachute or an empty backpack!

This trial is a great chance to talk about target validity: what are we asking & for why? bmj.com/content/363/bm…
First let me say I’m not an expert on target validity, because it’s a new concept. But I think this trial is a nice case study for it.

Check out the great paper introducing the concept, here: doi.org/10.1093/aje/kw…
So, what is target validity? When we do an #RCT, we want to know about the effect of a treatment *in a target population*.

Target validity tells us about how well we have learned about that from our trial (or observational study).
Read 21 tweets
BREAKING NEWS!!!

In the first ever randomized clinical trial, we demonstrated that parachutes did NOT prevent death or major injury compared to control in individuals jumping from aircraft.

Published today in @bmj_latest: bmj.com/content/363/bm…

#PARACHUTETrial #XmasBMJ
Deeply appreciative of all the efforts of all the PARACHUTE Trial Investigators.

A multicenter collaboration between @SmithBIDMC and @UM_MiCHAMP.

#XmasBMJ #PARACHUTETrial
Our editorial, behind the scenes of the trial, linked below.

N.B. to the public - please continue to use parachutes for skydiving.

blogs.bmj.com/bmj/2018/12/13…
Read 4 tweets

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