Discover and read the best of Twitter Threads about #Parkinsonsdisease

Most recents (10)

An elderly woman who would repeatedly count her dresses

1. 69-yr old lady was brought with 1-month history of repeated & excessive arranging and counting of dresses. Patient spent a lot of time searching for clothes & dresses and meticulously arranging them as per their sizes.
2. She would repeatedly count them. She would get up from sleep and repeat this act for several hours. On questioning, the patient agreed that this act of hers was irrational and unproductive, however, she expressed an inability to control her from doing so.
#MedTwitter
3. She had been diagnosed to have #Parkinsonsdisease 13 yrs ago. She was taking various medications including levodopa.
She had no prior history of psychiatric illness.
She was unable to sleep well, as she used to get up multiple times at nights to count her dresses.
Read 12 tweets
New work from the lab @NatureAging!❄️Lowering body temperature extends #longevity. We find that cold-induced #proteostasis prevents #aging and aggregation of proteins that cause age-related diseases #ALS #HuntingtonDisease in C. elegans and human cells nature.com/articles/s4358…
This was a tour de force by Hyun Ju Lee, @sedakoyuncu12, Hafiza Alirzayeva, @AlirezaBarandaq, and Amir Khodakarami (3 lab generations!). 1000x thanks to @impetusgrants for believing in us. Thanks to @CECAD_ @CGA_age @UniCologne @UKKoeln for their support
Aging is a major risk factor for neurodegenerative disorders linked with protein aggregation (#Alzheimers, #Parkinsonsdisease , #HuntingtonDisease, #ALS). We hypothesized that defining cold-induced changes can lead to converging modifiers of pathological protein aggregation🤔
Read 12 tweets
Trichloroethylene (TCE): An invisible cause of #Parkinsonsdisease (PD)

1. The incidence of PD has been increasing. Known risk factors such as genetic and head injury can't account for this increase in PD.
Exposure to TCE could be one of the factors causing an increase in PD.
2. TCE is a simple, six-atom molecule that can decaffeinate coffee, degrease metal parts, and dry clean clothes.
A small epidemiological study found that occupational or hobby exposure to the solvent was associated with a 500% increased risk of developing PD.
#MedTwitter Image
3. Exposure is not confined to those who work with the chemical. TCE pollutes outdoor air & groundwater, and contaminates indoor air. The molecule, like radon, evaporates from underlying soil and groundwater and enters homes, workplaces, or schools, often undetected.
Read 13 tweets
Less Than 6 Hours of #sleep a Night Linked to Serious, Chronic Illness
1. Beginning at age 50, those who slept 5 hours or less a night had a 30% higher risk of developing multiple chronic diseases over time than those who slept at least 7 hours a night.
#MedTwitter #MedEd
2. By the time the participants were aged 70 years, that risk had increased to 40%.
3. Higher risk was seen for #diabetes, #Cancer, heart disease, #stroke, COPD, chronic kidney disease, #liver disease, #depression, #dementia, #Parkinsonsdisease, and #arthritis.
Conclusion: It is important to get 7-9 hours of good quality sleep to reduce the risk of many chronic diseases.
(Ref: Less Than 6 Hours of Sleep a Night Linked to Serious, Chronic Illness - Medscape - Oct 21, 2022).
Read 3 tweets
#Thread
#IMPORTANCEOF #COCONUTOIL FOR #HEALTHYBRAIN AND #BODY

In the United States, an estimated 5.4 million people have been diagnosed with Alzheimer's disease. This figure is growing rapidly with the ageing population.

1
One of them was Steve Newport. His wife, Mary Newport, was a doctor. Dr. Mary learned that her husband had severe Alzheimer's disease.

When the doctor examined her husband at the hospital, he asked Steve to paint a clock. Instead, he drew a few circles and

2
then drew a few figures without any logic. It was not like a clock at all!.

The doctor pulled her aside and said: "Your husband is already on the verge of severe Alzheimer's disease!"

It turned out that it was a test of whether a person had Alzheimer's disease.

3
Read 18 tweets
Today is #purpleday. I was diagnosed with #epilepsy at the age of 28 after having simple partial seizures for years. I had tonic-clonic seizures -- what used to be called grand mal seizures -- in my sleep, and never knew.
This was diagnosed in a very classy way -- I woke up with a bruised forehead and a broken toilet seat. Things like stroke and brain cancer had to be eliminated. I had just moved to NYC and started writing for @CBSRadio. Bad timing.
There are more than 40 different types of seizures. They are very personal. They have different 'triggers'. Mine are triggered by exhaustion. I had to stop working overnights, and I avoid early mornings, which is difficult in a business that starts at 3am and goes all night.
Read 17 tweets
#MedicalNicotine

348,601 "ever-#snus users had about 60% lower Parkinson's disease risk compared with never-snus users."
academic.oup.com/ije/article/46…

30,000 British doctors followed for 60 years: "current smokers at baseline had a 30% lower risk of PD."
n.neurology.org/content/neurol…
#MedicalNicotine

Nicotine is beneficial for people with #ADHD. Research on adults and adolescents with ADHD shows that nicotine patches improve focus and attention, and reduce hyperactivity & impulsivity.
#MedicalNicotine

Nicotine reduces symptoms of Alzheimer's disease (AD).
d1wqtxts1xzle7.cloudfront.net/48014043/bf001…
Read 11 tweets
ADHD: "Nicotine ...may have properties similar to stimulant medications (e.g., Ritalin) used to treat ADHD. [It] may increase attention and reduce hyperactivity & impulsivity."
clinicaltrials.gov/ct2/show/NCT00…
#MedicalNicotine #ADHD #ADHDAwareness #Autism #Neurodiversity #Neurodivergent
ADHD: "The positive relation between ADHD & nicotine dependence is best explained by the self-medication hypothesis. This hypothesis ...is supported by ample evidence."
tandfonline.com/doi/pdf/10.108…
#MedicalNicotine #ADHD #ADHDAwareness #Autism #Neurodiversity #Neurodivergent
Read 5 tweets
LONG THREAD For my @projectlincoln friends & other interested parties my #coronavirus story continues-a story that has become both hysterically funny&incredibly hard. Don’t tell me not to “politicize” things – this is real life. For many reasons we have to get Mom & Dad home.../1
85 & 83 yrs old, #parkinsonsdisease #dementia & other conditions. Mom too weak 2 walk. No clear guidelines on how 2 keep them safe. Rented an #RV for a 1200 mi drive hoping to control their exposure. Tried 2 prepare the #RV for all potential needs. 2/
Have you ever put a sheet on a heavy foam mattress that's shoved between the bathroom wall & the kitchen? It’s like trying to put stockings on an elephant.Upside down.Stocked the fridge, have masks&gloves, praying for clear roads.Biggest issue is Mom’s confusion&increased fear /3
Read 15 tweets
So grateful to @TheFangGroupUiO and impressed with @NoAge100. Months ago, I told Evandro that @HorizonsHK invited me to beautiful #Norway. He responded with a request to keynote noage100.com/2019/08/17/nad… Image
At this conf, there were presentations on clinical testing of #nicotinamideriboside in #ataxiatelangiectasia, #Parkinsonsdisease, #frailty, #chemotherapyinducedcardiomyopathy & #amyotrophiclateralsclerosis, all premised on sound preclinical data and all based in beautiful Norway Image
Beyond that, they have strong interest/plans in #alcoholicliverdisease, #mildcognitiveimpairment & more. So impressed with the scientists, physicians & institutions in Norway that make this possible @Ahus_no @oslouniversity @ChromaDex #NR #NAD #Bergen #Tromsø #thebestisyettocome
Read 3 tweets

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