Discover and read the best of Twitter Threads about #Pathogenesis
Most recents (8)
1/5 "#SARSCoV2 #infection is associated with a #surprising number of #morbidities."
#amyloidogenesis #aΞ² #fibrils #COVID19 #SARSCoV2
#spike
#protein
pubs.acs.org/doi/10.1021/jaβ¦
#amyloidogenesis #aΞ² #fibrils #COVID19 #SARSCoV2
#spike
#protein
pubs.acs.org/doi/10.1021/jaβ¦
2/5 "#Uncanny #similarities with #amyloid-#disease associated #blood #coagulation and #fibrinolytic #disturbances together with #neurologic and #cardiac problems led us to investigate the #amyloidogenicity of the #SARSCoV2 #spike #protein (#S-protein)."
3/5 "#Amyloid #fibril #assays of peptide library mixtures and theoretical predictions identified seven #amyloidogenic #sequences within the S-protein."
1/4 "Using #PEPMatch, a newly developed #bioinformatics package which predicts #peptide similarity within specific #amino #acid mismatching parameters consistent with published #MHC binding capacity,..."
nature.com/articles/s4159β¦
nature.com/articles/s4159β¦
2/4 "... we discovered that #nucleocapsid #protein shares significant overlap with 22 #multiple #sclerosis (#MS)-associated proteins, including #myelin #proteolipid #protein (#PLP).Β
#MultipleSclerosis
#MultipleSclerosis
3/4 "Further computational evaluation demonstrated that this #overlap may have #critical #implications for #Tcell responses in #multiple #sclerosis (#MS) patients and is likely unique to #SARSCoV2 among the major #human #coronaviruses."
Did you miss the talk "Panorama of #lupus in 2020?" I did yesterday for @LupusEurope?
No worries, I'm starting a #tweeter #SLE #thread so that you can pick up the slides you're interested in π
Check below for the SLIDES β¬οΈ
No worries, I'm starting a #tweeter #SLE #thread so that you can pick up the slides you're interested in π
Check below for the SLIDES β¬οΈ
8 years since the first manuscript draft but it's finally here!
The interaction of #Ecoli O157β:H7 and #Salmonella Typhimurium #flagella with host cell #membranes and cytoskeletal components | #Microbiology #Pathogenesis #Thread
microbiologyresearch.org/content/journaβ¦
The interaction of #Ecoli O157β:H7 and #Salmonella Typhimurium #flagella with host cell #membranes and cytoskeletal components | #Microbiology #Pathogenesis #Thread
microbiologyresearch.org/content/journaβ¦
@strain9000 @ArielBlocker @MicrobioSoc This all started many πππππππππ ago...
Jo Elvidge and I were looking at the role of #flagella in early infection of #Salmonella and #Ecoli in relevant animal tissue models (ππ)
We spotted what looked like very intimate adherence...
Jo Elvidge and I were looking at the role of #flagella in early infection of #Salmonella and #Ecoli in relevant animal tissue models (ππ)
We spotted what looked like very intimate adherence...
It was a toughie to quantify back then with the tools we had, but every time we looked, we saw it π€
Very excited to share this work by the heroic team - @carolilucas Pat Wong @sneakyvirus @tiago21bio et al on βLongitudinal analyses reveal immunological misfiring in severe COVID-19β. A thread on our findings. #COVID19 #Pathogenesis (1/n)
nature.com/articles/s4158β¦
nature.com/articles/s4158β¦
In this study, we enrolled COVID+ patients and analyzed their immune responses and viral load over the course of their hospital stay. We also compared samples from COVID- healthy health care workers (HCWs) as comparison. (2/n)
As reported by others, we found that COVID patients with severe disease have low T cell numbers and increased monocytes and neutrophils. We also found eosinophils come up in patients. This is bizarre π§ (3/n)
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..."
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily.
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily.
With the #COVID19 outbreak, it is important to use language responsibly. Here is the first entry of our new #ContagiousWords series, defining the buzzwords and terminology dominating today's conversation. #Pandemic #PandemicsCost
@ilariacapua Language is powerful, so we must be sure and accurate in the ways we communicate science. #Epidemic #ContagiousWords #COVID19
#WSV2019 #Welcome_reception
Panel #discussion of the #prospective #plans of @WSVirology
#USA @uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc
Panel #discussion of the #prospective #plans of @WSVirology
#USA @uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc
@uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc #WSV2019 | #Janusz_Paweska | Wonderful Presentation of #South_African #mobile_laboratory_response to #Ebola outbreak in #West_Africa in the first meeting of WSV @WSVirology, #Stockholm 2019
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc @edrybicki
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc @edrybicki
@uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc @edrybicki #WSV2019 | Prof. #Ziad_Memish | #MERS_CoV an emerging #virus from the #ArabianPeninsula in the first meeting of WSV@WSVirology, #Stockholm 2019
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc #coronavirus #SaudiNationalDay #SaudiArabia @Alfaisaluniv
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc #coronavirus #SaudiNationalDay #SaudiArabia @Alfaisaluniv
