Discover and read the best of Twitter Threads about #Penicillin

Most recents (11)

I am going to write part of my (unfinished) story about the K to R transition as a woman in medicine and physician scientist in a multi-disciplinary research space in a tumultuous time. I am oversharing to encourage others in a similar 🚤#medtwitter #IDTwitter #AIMedEd. /1 of 20
I study #drug #allergy. It was the inferior antibiotic choices we made for people with vague antibiotic allergies during my residency @MGHMedicine @mghmedres that initially gave me the idea. Too often the allergy lists were impeding clinical care. /2 of 20
I hypothesized that drug allergies were a problem -- that penicillin allergies alone were linked to important antibiotic stewardship and public health outcomes. I set off to prove this, and address the burden of unclear drug allergies across populations. /3 of 20
Read 21 tweets
So jetzt die neuesten News : @Karl_Lauterbach @MarcoBuschmann @UNonnemacher @BMG_Bund
Bitte um Erklärung wo ich jetzt und sofort das #Penicillin fßr mein chronisch vorerkranktes Kind herbekomme denn das Medikament was sie täglich morgens und abends nehmen muss und das fßr die
2) nächsten Jahre,ist in keiner Dosierung mehr lieferbar! Nirgendwo!!!
Durch den Schulzwang Präsenzpflicht,wäre jede Infektion besonders mit SARS-CoV-2 lebensbedrohlich!!! Mehrere Apotheken haben bestätigt,dass sie bei allen bestellten Medikamenten Lieferschwierigkeiten hatten.
3) Eine davon hat 300 Medikamente nicht erhalten! Entweder sind sie wirklich so unwissend und uninformiert ßber die Zustände, was schwer vorstellbar ist, oder man muss ihnen Vorsatz unterstellen was noch durch Unterlassen gekrÜnt wird etwas zu unternehmen! Diese widerwärtige
Read 8 tweets
Tomorrow is #NationalPenicillinAllergyDay in the US! In advance of that, I will share some of my favorite resources on #penicillin #allergy. Please share these broadly with your networks. We have >30mil Americans to evaluate... let's get started! #NPAD 1/7 Image
@MGHAllergy has hosted a multi-site network called @USdrugallergy since 2017 and we have 7 engaged sites with 1,796 enrolled. On our website usdar.massgeneral.org we have @YouTube videos on #drugallergy and #penicillin allergy and post our latest research findings! 2/7
@AAAAI_org has a penicillin allergy center with easy links to educational videos and infographics. Educate yourself and your patients. Increase awareness with images for social media @allisoncramsey @AutumnGuyer education.aaaai.org/penicillin-all… 3/7 Image
Read 8 tweets
1 of 10 /Do you use an electronic health record? Did anyone ever teach you how to document #allergies? 👀Check our this #EHR allergy documentation guidance #medtwitter #idtwitter #AIMedEd @EricMacyMD @AutumnGuyer @allisoncramsey @vumc_cdsi_rsch @JACIInPractice
2 of 10/We are excited to announce that the adverse reaction to drugs biologics and latex (ARDBL) committee of the @AAAAI_org has an #inpress workgroup report on allergy documentation in the EHR. jaci-inpractice.org/article/S2213-…
3 of 10/ In this article: current state of allergy #ehr documentation, definitions, reconfigurations, and recommendations✔️#bestpractices in documentation for #penicillin allergy ✔️what to include and what not to include in the allergy list
Read 11 tweets
Weekend Digest

Name the pathogen

5 Clues
1. Gram-positive bacillus
2. Exudative #pharyngitis
3. #Scarlatiniform rash
4. Tolerance to #penicillin
5. Treat with #erythromycin Image
2/
#Arcanobacterium #haemolyticum

Gram + bacillus

Clinical: mild respiratory illness to a diphtheria-like disease.

Pharyngitis indistinguishable from Streptococcus pyogenes (Gram + coccus)

Many patients have blanching, erythematous, maculopapular “scarlatiniform” rash!
3/
#Arcanobacterium #haemolyticum is generally susceptible to penicillin, cephalosporin, carbapenem, macrolide, clindamycin, glycopeptide, gentamicin, ciprofloxacin, but resistant to TMP-SMX.

Tolerance to penicillin has been reported!

doi.org/10.1093/infdis…
Read 3 tweets
While COVID19 is grabbing world attention, another global public health threat is still rising in the wings - #AMR. By 2050 AMR could cause 10 million deaths if left unchecked. AMR is not new and its history stretches back long before penicillin. whatisbiotechnology.org/index.php/exhi… /1 Image
The first case of drug resistance was noted in 1907 by #PaulEhrlich, when he observed mice infected with Trypanosoma brucei developed resistance with repeated doses of #Salvarsan, the first compound found to have antimicrobial activity. whatisbiotechnology.org/index.php/exhi… /2 Image
Another drug spotted to cause resistance was Optochin, an antimicrobial agent used to treat pneumonia. The first instance of resistance was noted in mice, infected with pneumococcal bacteria, in 1910, and then in humans in 1913. /3 Image
Read 27 tweets
1/ #IDTwitter and #IDFellows, here is another #IDboardreview question: 20F p/w pharyngitis w/fever. There is no cough. Exam: Cervical adenopathy; tonsillar exudate. Rapid Strep antigen test pos. You start to prescribe her Amoxicillin but there is an allergy alert.
2/ She reports an allergic reaction to penicillin around age 8 or 9. She had a rash but no other symptoms. It resolved following discontinuation of med. She did not receive any treatment. Which of the following would you do next?
3/ Today we are going to talk about everyone’s favorite – #penicillin #allergy!
Read 14 tweets
Today is the start of #SHW2020! Each day this week, I'll be tweeting about Britain's long, tempestuous and ever-so-slightly bonkers love–hate relationship with its #sexualhealth.

Darlings, brace yourselves. 💋 #SHW20 Image
We begin with the Victorians, who, contrary to popular belief, were obsessed with sex. In the C19, the only known #STIs were syphilis and gonorrhoea. Diagnosis depended on observable symptoms (no blood tests/smears). Effective treatments were non-existent. Image: @ExploreWellcome Image
In 1864 the British government introduced the Contagious Diseases Acts, intended to protect the armed forces through 'regulation' of 'common prostitutes'. The Acts gave police almost-unlimited discretionary powers to arrest any woman they thought might be soliciting. Image: HCPP Image
Read 62 tweets
Antibiotics are commonly prescribed medications in the inpatient and outpatient setting and it's important to recognize #AdverseEvents, including idiosyncratic reactions, such as #encephalopathy.

2/
Antibitiotics associated with #Encephalopathy:
- Beta lactams
- #Cephalosporins (#Cefepime is the most common,
Ceftazidime)
- Imipenem
- #Penicillin procaine
- Fluoroquinolones
- Macrolides (clarithromycin)
- TMP-SMX
- #Metronidazole
- Isoniazid

3/
Read 14 tweets
The long #thread on How #China became global #antiobiotic supplier and it's effect on US. #penicillin #vitamins #generics #USFDA #chloramphenicol #WhiteHouse (1/22)
During the Civil War, #MaoZedong had seen his troops fell in large numbers by diseases like dysentery, which was fatal when penicillin was unavailable.

history.state.gov/milestones/194…

2/22.
North #China became the centerpiece of Chinese government’s larger, state-directed plan for self reliance on Chinese #antibiotics.

3/22.
Read 25 tweets
10 THINGS EVERYONE NEEDS TO KNOW ABOUT #SYPHILIS!

1️⃣ Syphilis is a Sexually Transmitted Infection, STI. So you get it mainly from having unprotected vaginal, anal or oral #sex!

{SHARE to create awareness!}
@DrOlufunmilayo @healthertainer ImageImage
2️⃣ Syphilis can also be gotten;

- from mother to her #fetus inside the womb

- through blood transfusion,&

- through breaks in the skin that come into contact with infectious lesions e.g. kissing a person with a mouth wound when you have a wound in your mouth!
3️⃣ #Syphilis may cause symptoms very similar to many other diseases. Hence it may be difficult to know you have syphilis.

That's why the disease is also dubbed "the great imitator"!
Read 11 tweets

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