Discover and read the best of Twitter Threads about #Permeability

Most recents (2)

Endothelial-derived microvesicles play a pathogenic role in vascular #inflammation, causing #endothelial barrier dysfunction by impairing adherens junctions and activating #neutrophils

More here: bit.ly/3g1FpH7
#Cardiotwitter #CardiovascularResearch

#Tweetorial below! Image
#Microvesicles (MV) are formed from the outward blebbing of the plasma membrane and carry a diverse cargo that regulate multiple processes.

During #inflammation these are produced by activated endothelial cells and released into the #circulation. TEM image of plasma MVs: (2/8) Image
In this study the authors investigated whether endothelial-derived MVs (EC-MVs) contribute to #vascular dysfunction during inflammation.

The authors used an animal model of #sepsis (CLP) and found that this increased EC-MV production (3/8) Image
Read 8 tweets
1/
Here’s a little thread about mobility & liveable neighbourhoods. I’ll call it

THE WOMAN & THE WALL

#Ballincollig has a magnificent park, the #RegionalPark. The park has riverside & woodland walks, playing fields, playgrounds, & historical buildings. It’s well used & loved. Image
2/
Recently, the central path in the park was extended to a new eastern entrance, making it accessible from new neighbourhoods.

Nearby residents want to use it. Image
3/
But what will people do when they are walled off from the most direct way to the park? Will they take the long way around?

Or will they do something else? Image
Read 11 tweets

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