Discover and read the best of Twitter Threads about #Pharmacotherapy

Most recents (5)

@VirusesMDPI #PedsICU fragile children, immunosuppressed patients, transplant recipients,or with onco-hematological, pulmonary, or cardiac comorbidities, might benefit from early treatment as soon as +ve #COVID test or asymptomatic…
Read 4 tweets
🧵of 🔟 #pharmacotherapy take home messages from #ESCCongress 22

1️⃣ Post MI - polypill (asp+ACEi+statin) improves 2º CV prev (SECURE)
2️⃣Antihypertensives can be taken AM or PM - no difference (TIME)
3️⃣Neprilysin inhibition doesn't affect cognitive function in HF (PERSPECTIVE) ImageImageImage
4️⃣ AHF, IV Acetazolamide + loop diuretics ➡️ better decongestion, ⬇️ hospital stay & discharge without residual volume overload. (ADVOR)
5️⃣ Dapagliflozin for patients with HFpEF / HFmrEF, and HFimpEF. (DELIVER)
6️⃣Allopurinol doesn't improve major CV outcomes in IHD. (ALL-HEART) ImageImageImage
7️⃣ Adjusted-dose VKA (not rivaroxaban) should remain the standard of care in patients with RHD & AF. (INVICTUS).
8️⃣The LIFE-HF model, Personalised lifetime predection of treatment benefit in HFrEF.
#ESCCongress ImageImage
Read 4 tweets
Fascinating @JAMANetworkOpen article on #schizophrenia treatments .. limits of #pharmacotherapy and benefits of added #psychosocial treatments. Here’s a snippet with eye towards how this relates to treating other mental health conditions. 1/4 @division_55…
“Among responders (to meds), some are able to function independently, others remain disabled despite control of their psychotic symptoms...residual disability attributed to negative symptoms and cognitive deficits, which are less responsive than psychosis to drug treatments.” 2/4
“persistence of disability and ↘️ quality of life, poor medication adherence necessitated delivery of evidence-based psychosocial services, including CBT; family psychoeducation; social skills training; assertive community treatment; and assistance w/work, education, housing” 3/4
Read 4 tweets
"A rational approach to #eCigarettes - challenging ERS policy on #TobaccoHarmReduction."
John Britton, Jacob George, .@LindaBauld, .@LeicesterLungs / Sanjay Agrawal, John Moxham, .@DeborahArnott, Ann McNeill, Nicholas Hopkinson
#EuropenRespiratoryJournal… Key messages for a rational approach to vaping and e-cigarettes
1) People #smoke #tobacco because of #nicotine addiction, but the major harms come not from the nicotine but from toxic substances in the smoke.
2) #Pharmacotherapy (e.g. dual #NRT or #varenicline) combined with psychological support should be made available to all #smokers to help them to quit and should be considered as the first line approach.
Read 11 tweets

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