Discover and read the best of Twitter Threads about #Preprints

Most recents (18)

#LongCovid es principalmente una vasculitis trombótica inducida por proteína Spike

Un estudio de caso de apoyo
#Guthilo🧵
#preprints
#MedTwitter
HT/: @angryhacademic

Muy, muy... interesante, lea hasta el final
Agradezco RT-❤
La COVID prolongada es una continuación de la patología que acompaña a la COVID aguda. 

Es importante destacar que no se pode rehabilitar hasta que se trate la patología.
Destacan el papel de los microcoágulos en la oclusión capilar, que los resultados coagulopáticos ocurren después de la covid aguda. Image
Read 20 tweets
#preprints
Paren todo que tengo un anuncio importantísimo
🥁🥁🥁🥁🥁🥁

La vacuna contra el SARS-CoV-2 de ciclo único obtiene una alta protección e inmunidad esterilizante en hámsteres
H/t @vipintukur
#MedTwitter Image
Un nuevo concepto de vacuna intranasal de ciclo único consolida la alta seguridad de una vacuna aplicada por vía intranasal que induce inmunidad esterilizante, que será clave para superar los brotes de SARS-CoV-2 en curso.
Los investigadores diseñaron "virus SARS-CoV-2 de ciclo único" (SCV) que carecen de genes virales esenciales, poseen características inmunomoduladoras superiores y proporcionan un excelente perfil de seguridad en el modelo de hámster sirio. Image
Read 12 tweets
🛑Secuelas pulmonares a los seis meses en niños con infección por SARS-CoV-2: estudio unicéntrico
H/t @EnemyInAState
#preprints
Via @medrxivpreprint
medrxiv.org/content/10.110…
Estudio descriptivo de centro único realizado en un hospital de atención terciaria del sector público en el norte de la India, desde junio de 2020 hasta octubre de 2021, estudiaron a niños de 7 a 18 años ingresados ​​con infección por SARS-CoV-2 y seguimiento durante 6 meses. Image
El 30% de los niños
( n = 12) presentó alteraciones de la función pulmonar, siendo en todos de patrón restrictivo.
Read 7 tweets
Février 2020 (article preprint envoyé à @olivierveran mais immédiatement censuré)
Des fragments #vih sans #SARSCoV2
zenodo.org/record/3724003
Février 2023
German Gov’t Bombshell: ‘Alarming Number of Vaccinated Are Developing AIDS’ hommage à #lucMontagnier newspunch.com/german-govt-bo…
Détails
Fev2020 fragments #HIV dans virus #COVID
preprint à @olivierveran pour l'informer
Il ne répondra jamais
Dès le lendemain le #preprints fut supprimé.
Puis nous publions aux #Indes.
C'est le 17 avril 2020 sur #cnews que #lucMontagnier lâche la bombe
Read 4 tweets
"It's another gut-punch to poor early career researchers".

The ARC have again raised extra barriers for ECRs, causing unnecessary delays & anxiety, wasting resources &, yes, …

Wasting. Tax-payer. Money.

Last year was #preprints, now it's #NITpicks.

Long 🧵 but stay with me🙏
The National Interest Test (NIT) was introduced by the previous Coalition Government.

It's a smoke screen for idealogical vetoing of humanities grants they want to parade in front of their supporters and ridicule, e.g.⤵️
smh.com.au/politics/feder…
It's an easy, lazy sell.

As "wise" former Minister @DanTehanWannon said, as he introduced it,

"NIT will give Minister of the day confidence to look Australian voter in the eye & say, ‘your money is being spent wisely’" ▶️parlinfo.aph.gov.au/parlInfo/searc…
Read 19 tweets
#ICYMI a revolution in #biodiversity monitoring is underway. This revolution is driven by independent technological advances - but even more so once those can be integrated

A 🧵to highlight just a few recent papers and #preprints

(📸 biodiversity wall (c) @mfnberlin) Image
1. environmental DNA (eDNA)

It's now possible to detect animals & other organisms through tracking their molecular traces 🧬. Originally developed for #freshwater animals 🐸(ncbi.nlm.nih.gov/pmc/articles/P…), the technology can now be adapted to almost every environment:

2/
e.g. very recent advancements include (A) sampling of eDNA from the air to detect #insects ...

3/
onlinelibrary.wiley.com/doi/full/10.10…
Read 19 tweets
Hey #ACC22 presenters, especially late breaking studies of consequence. If you don't have simultaneous peer-reviewed pub, consider #preprint what you presented so it's archived & accessible. Let’s make it normative. @medrxivpreprint @yaleHFdoc #LBCT @EricTopol @CMichaelGibson
@medrxivpreprint @yaleHFdoc @EricTopol @CMichaelGibson For all #ACC22 presenters, preprinting is easy; we accept scientific studies, screen rapidly, post quickly. Non-profit. It is of the community-available throughout the world, understood as pre-peer reviewed, and citable. Almost all reputable journals are fine with it, incl @NEJM.
@medrxivpreprint @yaleHFdoc @EricTopol @CMichaelGibson @NEJM In the pandemic @medrxivpreprint stimulated discussions about research in progress, & many examples of advancing research. Cardiology has not yet fully embraced it, yet is this work any less important? All fields should accelerate public scientific communication & #openscience.
Read 6 tweets
📢 Welcome to ar5iv.org

Change the "X" in any arXiv article link to the "5" in ar5iv to get a modern HTML5 document.

Thread: what is included, why now, and how we hope to merge back into arXiv.

#OA #OpenScience #preprints

1/10
What to expect?

A collection of 1.75 million preprints, readable today.
That measures at ~97% of the available sources.

Most documents mostly read well (~80%).
Few are perfect.
Almost all have a clear path to support.

2/10
Our own e-journal CSS:

- optimized for large screens, best in Firefox
- decent on mobile, in any browser
- justified text, with hyphenation
- dark/light themes (toggle with 🌙/☀️)
- highlighted notes
- basic figure zoom
- 1000+ lines of misc CSS elbow grease

3/10
Read 11 tweets
Our paper dropped: Performance Metrics for Comparative Analysis of Clinical Risk Prediction Models Employing Machine Learning. We show 'commonly reported metrics may not have sufficient sensitivity to identify improvement of
#ML models…’ @CircOutcomes ahajournals.org/doi/abs/10.116…
@CircOutcomes Risk models are ubiquitous now. In this paper, we 'propose the use of a comprehensive list of performance metrics for reporting and comparing clinical risk prediction models.’ Time to expand the metrics. @CircOutcomes ahajournals.org/doi/abs/10.116… @YaleMed @YaleCardiology @AHAScience
@CircOutcomes @YaleMed @YaleCardiology @AHAScience We review a wide range of options for assessing the performance of risk models and demonstrate the neccessity of a comprehensive view in any evaluation. Paper was led by Chenxi Huang. Also with @jbmortazavi; SL Normand; @jspertus @CesarCaraballoC @Dr_BowTie65 @DrJRums
Read 6 tweets
Hi friends at @ASAPbio_ and fans or preprints, I really need your help. I'm a bit fan of #preprints, but there is new development that if it finds copycats, will totally kill preprints at @biorxiv and @medrxiv. There is a journal at @mitpress, called 'Rapid REviews COVID19'. It..
downloads #preprints from @biorxiv and @medrxiv, and starts a formal peer review process, against the wishes of the authors, and then puts the reviews online. Our paper is already under peer review, and I really believe it should not be peer reviewed by @mitpress against our wish
Why is it a problem? 1) Imagine you have a controversial paper. It may become unpublishable, and in this way Rapid Reviews will have severely compromised the career chances of the postdocs and PhD students participating
Read 7 tweets
Hey tweeps, if you could reinvent the way we publish in science, what would you keep/change from the current model?
#science #PeerReview #publication #academia #research
So this thread is giving me a lot of good ideas. A colleague just sent me @ASAPbio_ . If you wanna see an overview of current #PeerReview and #Preprints experiments take a look here!

asapbio.org
@threadreaderapp unroll please!
Read 3 tweets
Clinical journal policies friendly for #preprints. Article led by @DaisySMassey now @JAMANetworkOpen… looks at top 100 journals & concludes 'clinical journals broadly supportive of considering clinical research preprints for publication.’ jamanetwork.com/journals/jaman… @medrxivpreprint Image
@DaisySMassey @JAMANetworkOpen @medrxivpreprint "After classifying each journal according to the content of its preprint policies, we found that 86% of these journals allow for submitting articles previously posted as preprints.” @DaisySMassey @JAMANetworkOpen @medrxivpreprint
@DaisySMassey @JAMANetworkOpen @medrxivpreprint And just kudos to @DaisySMassey; we are so fortunate to have talented postgraduate research assistants who make us better, do outstanding work, and continually exceed our high expectations. She led this effort and stay tuned for other good work from her.
Read 3 tweets
so now ive published my paper on a #preprint (osf.io/preprints/nutr…), its worth comparing my experience with typical #peerreview publishing, mainly to highlight how much time & energy we waste with a system that offers very little added value
1/9
#openscience #AcademicTwitter
il do this comparison with the last paper i got formally accepted to a journal as these 2 co-occured so there's no "time effect" or anything as a confounder. (JP = journal publishing; PP = preprint publishing) 2/9
JP: rejected 6 times (i think); 3 were editorial rejections *explicitly* mentioning the null findings as a reason for rejection
PP: paper is out there open for anyone to openly critique and i welcome this 3/9
Read 9 tweets
why i am no longer publishing (my own) #research in #academic journals - a (long) thread 1/38

#AcademicTwitter #AcademicChatter #academicpublishing #academicjournals #peerreview #ecrchat #OpenScience #publicationbias

(some references at the end of the thread)
(i still have a few collaborative papers to write and these will be published properly for the benefit of my co-authors)

i will soon publish a paper on a pre-print server, with no intention of submitting to an academic journal. my reasons for this are manifold 2/38
1. #academia is inherently corrupt & the publication model facilitates this:
- unpaid labour (editors, peer-reviewers,& authors [ok, they do get paid by the uni which oft = public funds yet journals privately profit & we see none of this unlike other forms of publishing]) 3/38
Read 45 tweets
Kudos to @MartinLandray and team, including all patients, practitioners, administrators, funders & researchers. Amazing study. This is the new standard about how to move quickly, thoughtfully and effectively in research. Now @medrxivpreprint. Pls comment. medrxiv.org/content/10.110… Image
@MartinLandray @medrxivpreprint This is a landmark event for #preprints. Major study opting to post @medrxivpreprint for comments so investigators & other interested parties around world can see the study and comment. Rapid communication. Complementary to peer-review publication. Thankyou #RECOVERYtrial team.
Also appreciation to all the journals that are now on board with #preprints. Almost all are supportive. We have come a long way… soon perhaps everyone will preprint at time of submission as they do in so many other fields. @jsross119 @cshperspectives @TheoBloom @JohnRInglis
Read 3 tweets
We’ve just had a paper published and I would like to tell you a story about people in science being nice to each other – a thread cell.com/cell/fulltext/…
This is a large, collaborative effort – 54 authors across multiple institutions, led @MountSinaiNYC and @CVRinfo. But the science in the story is quite simple (and you can read it in the paper), so I’ll explain it quickly before telling a different story (which you cannot)
Briefly, here’s the science of it. THE BACKGROUND: (i) Viruses need to make mRNA that host ribosomes can translate into proteins Baltimore classification of viruses
Read 35 tweets
At #FORCE2019 @npscience getting everyone warmed up for a panel on "Who will influence the success of #preprints in biology and to what end?"
@npscience . @npscience laid important foundations for the discussion: (1) be aware of stakeholders' cultural backgrounds and the influences on the their viewpoints; and (2) it's always a balance between individual vs collaborative gains. #Force2019
@npscience First panelist @ReaderMeter compared #preprints to a staging area, akin to how we would interact with an #opensource project, where all sorts of collaboration could happen and #openscience practised 🌟 #Force2019
Read 13 tweets
The view expressed below is part of what holds science back.

If you are privileged to have access to a "few colleagues" or be one of those colleagues, then the status quo works well for you. #PrePrint articles make this more seamless, & more equitable/

The position of #PrePrint = not peer reviewed = rubbish, is also dated. We all know how hit and miss peer review can be. We also know how timely communication, with time stamping and dissemination, that is under the control of the authors (rather than a journal) is valuable.
For those of you who have not experienced peer review yet - we have a system in science where we ask our colleagues to review our publications. Our colleagues receive no money for this work (usually) and this is done all within confidential systems (managed by the journals).
Read 19 tweets

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