Discover and read the best of Twitter Threads about #Prodige7

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Finally, #Prodige7 results are out at @TheLancetOncol!

This is a giant step forward building evidence on Peritoneal Metastases of CRC origin.

French groups have to be congratulated for this outstanding work.

@RENAPE_Network & @GroupeUNICANCER-GI

doi.org/10.1016/S1470-… Image
#Prodige7 is the 1st prospective study to report these excellent survival outcomes in PM of CRC origin:
-Median OS: 41'2-41-7 months
-1y OS: 86'9-88'3%
-5y OS: 36'7-39.4%
Relapse-free survival is astonishing too:
-Median RFS: 11'1-13'1 months
-1y RFS: 46'1-59%
-5y RFS: 13'1-14'8% Image
Although there is no difference regarding OS, RFS or PFS between cytoreductive surgery alone VS Oxaliplatin-based HIPEC.

There is room for hope and new research regarding PCI 11-15 where HIPEC does better in OS and RFS than surgery alone. ImageImageImage
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