Discover and read the best of Twitter Threads about #Recombinant

Most recents (4)

New #PANGO designations - BA.2.*

BA.2.4Alias of B.1.1.529.2.4, #Singapore lineage

BA.2.5Alias of B.1.1.529.2.5, lineage in #Portugal and other countries

BA.2.6Alias of B.1.1.529.2.6, lineage in #France and other countries

BA.2.7Alias of B.1.1.529.2.7, #USA lineage ImageImage
These are new designations - branching from the BA.2 subvariant

more to follow ..... will update key mutational differences and transmission advantage (if any)
BA.2.4 (aka B.1.1.529.2.4) | prevalent in Singapore

Key mutation: ORF6:M58K

COV-spectrum predicts a growth advantage of 14% over BA.2 and 46% over BA.1.1 in #Singapore

BA.2 and BA.1.1 are currently the dominant lineages in circulation in Singapore Image
Read 29 tweets
Tracking sequences with both #omicron and #delta signatures

Flagged by @GISAID as "ML" sequence under investigation (#Recombinant or #Contamination ?)

Sequences are under investigation: 4511

Tracker: tinyurl.com/4cbpnz46 Image
#USA has 2423 sequences under investigation from multiple laboratories.

They contain signatures from both #Delta and #omicron #variants

ML sequence #hotspots: #California, #Texas, #NewYork, #Arkansas and #Minnesota

#deltamicron or #deltacron or #contamination? ImageImageImage
#India has 568 sequences under investigation from multiple laboratories.

They contain signatures from both #Delta and #omicron #variants

ML sequence #hotspots: #Karnataka, #TamilNadu, #Maharashtra, #Gujarat, #WestBengal, #NewDelhi

#deltamicron/#deltacron or #contamination? ImageImageImage
Read 7 tweets
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..." ImageImageImage
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964 ImageImageImageImage
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily. ImageImageImageImage
Read 68 tweets
#SARSCoV2 There are several kinds of #vaccines, whereby all share the goal of generating adaptive #immunity via 1) #antibodies via B cells, and 2) T-cell receptors (#TCRs) via T cells:
1) live-attenuated, where you produce an actual #virus in an egg or cell line
2) #recombinant, where you introduce #DNA into yeast, bacteria, or cell lines — you produce pieces of the #virus #proteins, then either administer them as-is or typically by linking them to immunogenic substrates like albumin, BSA and KLH
Read 6 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!