Discover and read the best of Twitter Threads about #RheumJC
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Here is my attempt at organizing the massive number of replies to my request for physicians on Twitter to follow for my #MPLSVAGrandRounds talk “Social Media in Medicine”
Here is the original thread, which has lists of people in just about every specialty you could think of, and quickly went beyond my ability to organize.
When going through these lists, @Doctor_V reminded me this important point:
@BeckySueToo @RheumJC Let me explain...
@BeckySueToo @RheumJC What is wrong here is using total B cells. There are sunsets of CD19. Broadly speaking: naive (have not received Ag stimulation, not activated and no T cell help); memory (antigen experiences, been in a terminal centre) and plasmablast (trying to become a plasma cell)...
@BeckySueToo @RheumJC In healthy people B cells are about 2/3 naive, 1/3 memory, 1-2% plasmablast. But in autoimmune diseases this changes. In SLE the hallmark is expansion of the plasmablasts, up to 5 or even 10%. Makes sense, right? #rheumjc
