Discover and read the best of Twitter Threads about #ScienceResearch

Most recents (8)

Have LED lights reduced #LightPollution, or have things gotten worse because of blue light emissions? We have the answer, and it's not good news...

🧵 below, full methodology and results new in @sciencemagazine: science.org/doi/10.1126/sc… #ScienceResearch
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Before I tell you what we did, I want you to understand why this is important. Skyglow is a visible symbol of our failure to transition to a sustainable society.

In addition, if skyglow is growing, then all of the ecological impacts of #LightPollution are probably too. (2/) Image showing sky brightness 60 km South of Berlin (left) an
So what did we do? It all starts with the #CitizenScience project Globe at Night (GaN), which you've probably seen me boosting before. In GaN, participants select which of a set of star charts most closely matches the sky they see. (3/) Globe at Night star maps
Read 50 tweets
I'm super excited to share my 1st first-author paper now out in @ScienceMagazine, where we tackle an age-old question in microbiology: How do dormant spores decide to wake up? Turns out that they can count in their sleep using electricity!😴⚡️
science.org/doi/10.1126/sc…
Bacterial spores are a special type of cell that look and function like microscopic plant seeds: a hyper-resilient DNA bunker that aims to weather bad conditions and reemerge in a better future. They are metabolically dormant, and by all practical means, pretty much dead.
Because of their extreme resistance to most stresses (like heat, UV, dryness, antibiotics), gaining a better understanding of spores has huge implications in healthcare, food safety, and biotechnology.
Read 18 tweets
5 years ago, I proposed using #DeepLearning to predict response to immunotherapy in TCR-Seq.
🧬🧬🧬🧬
Last year, we published #DeepTCR. Today, I am proud to share its application in cancer immunology, now out in @ScienceAdvances #ScienceResearch
🔶🔷🔶🔷
science.org/doi/10.1126/sc…
This project started with a hypothesis that if a specific antigen-specific response was characteristic of responses to immunotherapy, then this should be reflected in the TCR repertoire/sequences.

After all, the TCR repertoire is ground truth for the antigen-specific response.
First, we expand the #DeepTCR framework by allowing featurization of the TCR in context of the HLA background it is found within, overcoming the challenge in making direct comparisons of TCR repertoire in HLA mismatched individuals. Image
Read 21 tweets
Our paper in which we demonstrate the vast tunability of optical interactions between levitated glass nanoparticles is published in Science! science.org/doi/10.1126/sc… #ScienceResearch 🧵1/18
Researchers in levitated optomechanics aim to exploit some of the unique features of #opticallevitation for novel quantum control techniques in order to create macroscopic quantum states of the particle motion. 2/18
One such feature is that particles smaller than the laser wavelength behave as “dipoles”: they polarize in phase with the laser. The particle radiates some of this light – like an antenna – in phase with the trapping laser as well. This is what we call “coherent scattering”. 3/18
Read 18 tweets
What do the diets of ice age mammals tell us about the biodiversity crisis?

Our new research in @ScienceMagazine asks how extinction and range loss have affected land mammal food webs globally over the last 130,000 years 🧵

#ScienceResearch science.org/doi/10.1126/sc… An illustration of mammal species that would naturally occur
We show how declines in land mammals have rippled across the web of life by degrading food webs

We chart what we’ve lost, what more we’ll lose if endangered species go extinct, and what potential exists for reversing losses by restoring extant mammals to their historic ranges A photo of three lions cubs together on a rock in Tanzania.
Some background: Predator-prey interactions are part of the web of life that sustains the diversity and resilience of our ecosystems. Recent animal declines and food web disruption show the consequences of food webs unravelling

But animal declines aren’t only a new thing... Photo showing a pair of cheetahs taking down an impala in So
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We analyzed 4.4 million @Team_eBird records to find out why tropical birds live in narrow slices of mountainside

You won’t BELIEVE what we found

Out today in #ScienceResearch

science.org/doi/10.1126/sc…

w/ @StrimasMackey & @EliotITMiller Image
But first the backstory.

As you travel up or down a tropical mountain, you will find very different species in each elevational zone. Way more so than on temperate zone mountains. This species turnover explains why tropical mountains are Earth’s hottest biodiversity hotspots Image
We began studying this puzzle 15 yrs ago in tropical Andes

Want to find different tanagers, antpittas, or hummingbirds? Move 500 m up or downslope. Exciting! And puzzling! Forests often look similar and birds have wings. Why don’t they live in broader elevational ranges? ImageImage
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A pinch of pinscher, a dash of 'shund... a pint of pittie for good measure, and what kind of #dog do you get?
Ulti-mutt-ly: a distinct individual.

Happy to share our article on dog genomes, behavior, and MUTTS in @ScienceMagazine! @UMassChan @broadinstitute #ScienceResearch 1/n
Even the most mixy of #mutts cannot escape the question: what's in the sauce? For the first time, we unravel the genomes of mutts (1500+ dogs of mixed or mystery heritage) and what they can show us about the inheritance of behavior. 2/n
Research was made possible thanks to the thousands of dogs enrolled in our Darwin’s Ark project (darwinsark.org). @darwinsarkfnd

See: dog tax attached #communityscience #citizenscience #CitizenScienceMonth 3/n
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Perceptions of #dog breed temperments are ingrained in our culture. Breed #stereotypes play out in dog parks, show up in city ordinances & leases, are celebrated at dog shows, and infuse Hollywood movies... but what if I told you dog temperment doesn't work like that? 1/n Morpheous from the Matrix "But what if I told you"
ANNOUNCING OUR NEW, AT-LEAST-8-YEARS-IN-THE-MAKING-BUT-WHO'S-COUNTING, +FANCY-GENOMICS #DOG temperment PAPER!!!! @UMassChan @broadinstitute @karlssonlab @darwinsarkfnd #ScienceResearch @iaabc 2/n science.org/doi/10.1126/sc… Image of tweet showing April 29 issue of Science with a phot
Before I unpack our findings, I have a conflict of interest to disclose: I AM A CAT PERSON. 3/n
Read 19 tweets

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