Discover and read the best of Twitter Threads about #Sequence
Most recents (16)
Are you interested in learning about #bioinformatics and working with #genomic data? Here's a detailed #learning path to get you started:
To build a strong foundation in biology, you'll need to learn about:
The #structure and #function of #cells, including the various #organelles and their roles in the cell. This will help you understand how cells work and how they carry out essential functions such as #metabolism and #energy production.
🧵🧵 THREAD: #Bioinformatics and #AlphaFold 🧵🧵
1. #AlphaFold is a deep learning system developed by #DeepMind, to predict the 3D #structure of #proteins from their #aminoacid sequence.
2. #AlphaFold has been applied and tested extensively in the biennial #CASP (Critical Assessment of protein Structure Prediction) experiment, and has achieved state-of-the-art performance.
🧵#Bioinformatics applied to genomics, a THREAD🧵🧵:
#Genomics is the study of the entire #genetic makeup of an #organism, including its #DNA sequence, #gene structure, and regulation of #gene #expression.
#Bioinformatics is the application of computational techniques, such as #machine #learning and data mining, to the analysis of large datasets of biological information, such as #genomic, #proteomic, and #metabolomic data.
Are you interested in getting started in #bioinformatics but not sure where to begin? Here are some tips to help you get started on your journey. A THREAD🧵🧵:
Start by learning a high-level #programming language, such as #Python or #R, and familiarizing yourself with data structures and #algorithms commonly used in #bioinformatics. The #BioPython and #Bioconductor libraries are great resources for this.
#COVID19 #VariantDashboard - #UnitedStates
TOP lineages (15-DAY TRENDS):
23.39% BA.2.12.1, <- Spike:L452Q
19.16% BA.2,
14.85% BA.2.9,
12.25% BA.2.10,
10.79% BA.2.12,
9.43% BA.2.3 and
2.33% BA.1.1
Tracker (by State): tinyurl.com/mryj4uu7
#OmicronUpdates 04/30/22
TOP lineages (15-DAY TRENDS):
23.39% BA.2.12.1, <- Spike:L452Q
19.16% BA.2,
14.85% BA.2.9,
12.25% BA.2.10,
10.79% BA.2.12,
9.43% BA.2.3 and
2.33% BA.1.1
Tracker (by State): tinyurl.com/mryj4uu7
#OmicronUpdates 04/30/22
#OmicronVariantUpdates #UnitedStates 04/30/22
Top circulating #sublineages: BA.2.12.1, BA.2*, BA.2.9, BA.2.10, BA.2.12, BA.2.3, and BA.1.1
* includes recently designated BA.2.x.y
Top circulating #sublineages: BA.2.12.1, BA.2*, BA.2.9, BA.2.10, BA.2.12, BA.2.3, and BA.1.1
* includes recently designated BA.2.x.y
Sequence count by Division - #UnitedStates 04/30/22
#NewYork, #NorthCarolina, #Arizona, #California and #Connecticut have submitted >125 sequences with sample collection dates between April 15 to April 30, 2022.
#NewYork, #NorthCarolina, #Arizona, #California and #Connecticut have submitted >125 sequences with sample collection dates between April 15 to April 30, 2022.
#COVID19 #VariantDashboard - #UnitedStates
BA.2.12.1 is the top circulating lineage in the USA
Its not the dominating strain yet by looks like it will get there in 2-3 weeks!
Tracker (by State): tinyurl.com/mryj4uu7
#OmicronUpdates 04/29/22
BA.2.12.1 is the top circulating lineage in the USA
Its not the dominating strain yet by looks like it will get there in 2-3 weeks!
Tracker (by State): tinyurl.com/mryj4uu7
#OmicronUpdates 04/29/22
#COVID19 #VariantDashboard
TOP lineages (15-DAY TRENDS) - #UnitedStates:
23.76% BA.2.12.1, <-S:L452Q
19.22% BA.2,
15.47% BA.2.9,
11.81% BA.2.10,
10.45% BA.2.12,
9.31% BA.2.3 and
2.64% BA.1.1
Tracker (by State): tinyurl.com/mryj4uu7
#OmicronUpdates 04/28/22
TOP lineages (15-DAY TRENDS) - #UnitedStates:
23.76% BA.2.12.1, <-S:L452Q
19.22% BA.2,
15.47% BA.2.9,
11.81% BA.2.10,
10.45% BA.2.12,
9.31% BA.2.3 and
2.64% BA.1.1
Tracker (by State): tinyurl.com/mryj4uu7
#OmicronUpdates 04/28/22
*Typo corrected: Its not the dominating strain yet *but* looks like it will get there in 2-3 weeks!
#PROTOKOLL - aufgenommen in der öffentlichen Sitzung des #Landgerichts #Ravensburg, 4. #Zivilkammer, am Donnerstag, 12.03.2015 in Ravensburg
pdfhost.io/v/SQAEREtoi_Pr…
#virus #genome #sequence #genomsequenz
pdfhost.io/v/SQAEREtoi_Pr…
#virus #genome #sequence #genomsequenz
Complete Genome Sequence of a Wild-Type Measles Virus Isolated during the Spring 2013 Epidemic in Germany
Artikel [Englisch]: pdfhost.io/v/GX59BTyJT_Co…
Google Übersetzung: pdfhost.io/v/2WkFtgJo0_Vo…
Source: edoc.rki.de/handle/176904/…
#virus #genome #sequence #genomsequenz
Artikel [Englisch]: pdfhost.io/v/GX59BTyJT_Co…
Google Übersetzung: pdfhost.io/v/2WkFtgJo0_Vo…
Source: edoc.rki.de/handle/176904/…
#virus #genome #sequence #genomsequenz
Outbreak of Measles Among Persons With Prior Evidence of Immunity, New York City, 2011
Artikel [Englisch]: watermark.silverchair.com/ciu105.pdf?tok…
Google Übersetzung: pdfhost.io/v/7BgWqor42_Au…
Source: academic.oup.com/cid/article-ab…
#virus #genome #sequence #genomsequenz
Artikel [Englisch]: watermark.silverchair.com/ciu105.pdf?tok…
Google Übersetzung: pdfhost.io/v/7BgWqor42_Au…
Source: academic.oup.com/cid/article-ab…
#virus #genome #sequence #genomsequenz
Just a friendly reminder @moderna_tx told the @SECGov that the @US_FDA defines #mRNA as gene therapy. And called it an unprecedented new category of #medicines tho they really want that #vaccine classification anyways for liability protections & fear the public wouldn’t take it.
Want to learn about a gene function, but there’s no functional data in your species of interest? Or maybe looking for a homologue of your fav gene in a model organism to carry out functional work? Look no further! This #tweetorial will show you how to find orthologues in @ensembl
2/14
Let’s start on the Ensembl homepage and search for our #gene of interest SCP2 by typing its name into the search box. Then go to the gene tab by clicking on the gene name in the search results.
#Ensembltraining #genomics #bioinformatics #EnsemblCompara
Let’s start on the Ensembl homepage and search for our #gene of interest SCP2 by typing its name into the search box. Then go to the gene tab by clicking on the gene name in the search results.
#Ensembltraining #genomics #bioinformatics #EnsemblCompara
3/14
You can learn more about the #gene function by exploring gene ontology terms and associated phenotypes. Let’s click on Phenotypes in the side menu. This view shows phenotypes associated with our gene of interest and variants in this gene.
You can learn more about the #gene function by exploring gene ontology terms and associated phenotypes. Let’s click on Phenotypes in the side menu. This view shows phenotypes associated with our gene of interest and variants in this gene.
@TaschaLabs @radixdlt @im_jakescott
#HEADER 0/1 #sequence S=1 #Subject #Comment = my own comments not Tasch or other part quotes, which also close with "
Origin - see 0/0/0
0/m/n
0/1/0
m = 1
n = 11
#HEADER 0/1 #sequence S=1 #Subject #Comment = my own comments not Tasch or other part quotes, which also close with "
Origin - see 0/0/0
0/m/n
0/1/0
m = 1
n = 11
@TaschaLabs @im_jakescott @radixdlt #Logic
1/n
I have no concerns about the team delivering
I’m sure there will be difficulties and decisions to be made on the road from theory —> working PoC —> scheduled milestone release
That’s reality for you
Found here reddit.com/r/Radix/commen…
1/n
I have no concerns about the team delivering
I’m sure there will be difficulties and decisions to be made on the road from theory —> working PoC —> scheduled milestone release
That’s reality for you
Found here reddit.com/r/Radix/commen…
@TaschaLabs @im_jakescott @radixdlt #Logic
2/n
Radix is in a unique position at the moment. The way the limits of the problem domain are technically defined is in terms of decentralisation, scalability and security.
2/n
Radix is in a unique position at the moment. The way the limits of the problem domain are technically defined is in terms of decentralisation, scalability and security.
(1/7) A quality control tool for raw #sequence data. Using #FastQC you may check:
🚀 Per base sequence #quality (do you see a drop in sequencing quality near the read end?). This view shows an overview of the range of quality across all bases at each position in the FASTQ file.
🚀 Per base sequence #quality (do you see a drop in sequencing quality near the read end?). This view shows an overview of the range of quality across all bases at each position in the FASTQ file.
(2/7) Per sequence quality scores (how many reads are the best?) The per sequence quality score report shows whether a subset of sequences has universally low-quality values.
(3/7) Per base sequence content (the proportion of each base position in a file for which each of the four normal #DNA bases has been called). Ideally, in a random library, we would see four parallel lines representing the relative base composition.
Real Rates aren’t gonna be this low forever...Break Evens Lead with Copper. #Reflation
10 yr tsy bonds to moon trade. Crowded like 10 year Tsy Bonds to Zero crowd back in Fall ‘18..Scary Charts back then now it’s Scary Charts to Zero Yields. Truth probably somewhere in middle. CFTC Spec 10 Yr Govt. Bond Longs now ripping to +31K.. vs -756K Short in Fall 18.
#DV01
#DV01
Bird’s-eye view 👁 on what to look out for @WCGIC #WorldGI2020.
Opening remarks on important data 📺 @myESMO - by Dr. Eric Van Cutsem @UZLeuven.
🟩Good to see more #PrecisionMedicine🧬
🟥#Immunotherapy #Immuno-#oncology
🟦TNT & other chemo strategies
@Annals_Oncology #OncoAlert
Opening remarks on important data 📺 @myESMO - by Dr. Eric Van Cutsem @UZLeuven.
🟩Good to see more #PrecisionMedicine🧬
🟥#Immunotherapy #Immuno-#oncology
🟦TNT & other chemo strategies
@Annals_Oncology #OncoAlert
🆕#ctDNA #liquidbiopsies 🩸🧬
👀 👇🏾at the number of #clinicaltrials cropping up in this space‼️
🇦🇺DYNAMIC-II
🇦🇺DYNAMIC-III
🇺🇸COBRA @NRGonc
🇺🇸BESPOKE
🇺🇸@SU2C
🇯🇵 CIRCULATE
🌎COLUMBIA
🇮🇹🇪🇸PEGASYS
🇬🇧TRACC
🇩🇪CIRCULATE
🇫🇷crEATE
🇩🇰IMPROVE-IT
We have 2🇺🇸studies open. #CRCSM #WorldGI2020
👀 👇🏾at the number of #clinicaltrials cropping up in this space‼️
🇦🇺DYNAMIC-II
🇦🇺DYNAMIC-III
🇺🇸COBRA @NRGonc
🇺🇸BESPOKE
🇺🇸@SU2C
🇯🇵 CIRCULATE
🌎COLUMBIA
🇮🇹🇪🇸PEGASYS
🇬🇧TRACC
🇩🇪CIRCULATE
🇫🇷crEATE
🇩🇰IMPROVE-IT
We have 2🇺🇸studies open. #CRCSM #WorldGI2020
#WORLDGI2020 This is 🆒 ☢️ 32-P EUS-guided implantation in #pancreascancer #PANCSM @myESMO @WCGIC @Annals_Oncology.
Still miles to go. OS median of 16 months pointing again to the systemic nature of disease. Need to piggyback these local approaches to better systemic. #OncoAlert
Still miles to go. OS median of 16 months pointing again to the systemic nature of disease. Need to piggyback these local approaches to better systemic. #OncoAlert
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..."
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily.
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily.
"If I were to write a textbook on #complexity, it would be structured like this..."
- SFI Pres David Krakauer starts off this morning at #CSSS19 #CSSS at @IAIASantaFe
#error #adaptation #universality #coarsegrained #math #theory
- SFI Pres David Krakauer starts off this morning at #CSSS19 #CSSS at @IAIASantaFe
#error #adaptation #universality #coarsegrained #math #theory
"If you talk about #intelligence and #stupidity, you talk about #communication and #policy. That is the natural place to start."
"If you've ever written a Lokta-Volterra #equation, you've drawn a perpetual motion machine. There's no #dissipation."
- SFI President David Krakauer
"If you've ever written a Lokta-Volterra #equation, you've drawn a perpetual motion machine. There's no #dissipation."
- SFI President David Krakauer
Two new postdoc positions now open to work in our group at @CCDD_HSPH
@CCDD_HSPH One is on a cool new project to incorporate pathogen #sequence data in to analysis of #vaccine #efficacy #trials .
academicpositions.harvard.edu/postings/8296
academicpositions.harvard.edu/postings/8296
Another on flexible topics including but not limited to #AMR (especially as it relates to #vaccines), dynamics of multistrain pathogens, or #vaccine #trial modeling academicpositions.harvard.edu/postings/8298
