Discover and read the best of Twitter Threads about #SpatialProteomics

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Amazing week for #DeepLearning in #spatial #singlecell biology, with 2🔥new Graph Neural Networks methods!

1.STELLAR🇺🇸 @jure: a cell type annotation & discovery atlas-type framework
2.NCEM🇪🇺 @fabian_theis: an approach to infer cellular communication patterns

Deep dive below🧵 Image
But first, some background.

Spatial molecular biology has actually been around since the 70s. @lpachter's wonderful book-like article "Museum of Spatial Transcriptomics" comprehensively discusses history, tech & methodology advances in the past 50 years.
nature.com/articles/s4159…
Nevertheless, recent advances in single cell molecular technologies (brought by e.g. @10xGenomics & @AkoyaBio) have facilitated the high-throughout profiling of (groups of) single cells in their tissue context across embryogenesis, normal tissue development & disease progression.
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