Discover and read the best of Twitter Threads about #SubstanceSaturdays
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🚀💊 Get ready for an incredible journey into the world of #methamphetamine! Did you know it was originally used to keep soldiers alert in WWII? Let's explore its fascinating history and impact on society on this week's #SubstanceSaturdays⚠️
🔍 First synthesized in 1893, methamphetamine is a central nervous system stimulant. It gained popularity for various purposes, including treatment of ADHD, obesity, and narcolepsy. Its use skyrocketed during WWII, where it was given to soldiers to stay awake and alert 🌍💣
💊👩⚕️ Pharmaceutical use of methamphetamine peaked in the 1950s-60s under the brand name Desoxyn. The FDA still approves it today for treating ADHD and exogenous obesity, but its use is highly controlled due to its potential for misuse. It's a Schedule II drug 🚨📋
#SubstanceSaturdays ❄️
1/ #Cocaine is a powerful stimulant drug that has been around for thousands of years. It was originally used by indigenous people in South America for religious & medicinal purposes, and was later introduced to Europe and the US in the late 19th century.
1/ #Cocaine is a powerful stimulant drug that has been around for thousands of years. It was originally used by indigenous people in South America for religious & medicinal purposes, and was later introduced to Europe and the US in the late 19th century.
2/ Cocaine works by increasing levels of #dopamine, a neurotransmitter that regulates pleasure and reward, by blocking its reuptake leading to an accumulation in the synpatic cleft. This leads to feelings of euphoria, increased energy and alertness, and decreased appetite.
3/ Serotonin and norepinehphrine reuptake are also inhibited, leading to increases in those neurotransmitters as well. Sodium channels are also blocked, slowing down the action potentials, thus leading to its medical use as a local anesthetic.
Let's uncover something with #SubstanceSaturdays
1/ #Xylazine is a sedative and analgesic drug that is commonly used in veterinary medicine to sedate and immobilize animals. It is also used as an anesthetic in laboratory animals and as a tranquilizer in horse racing.
1/ #Xylazine is a sedative and analgesic drug that is commonly used in veterinary medicine to sedate and immobilize animals. It is also used as an anesthetic in laboratory animals and as a tranquilizer in horse racing.
2/ Xylazine is a Schedule III controlled substance under the United Nations Convention on Psychotropic Substances, meaning that it has a potential for abuse and dependence, and it should be used under strict medical supervision. One of its nicknames is "#tranq".
3/ Unfortunately, Xylazine is being used to contaminate the drug supply, and it is being sold as a street drug. This is a dangerous practice as Xylazine can cause serious side effects, including respiratory and cardiovascular depression, and even death in high doses.
