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1/As promised & after reading $CRSP latest Q4 2022 #financial #report here is my impression regarding @CRISPRTX latest corporate status. I have focused only on the main issues that I found to be the most interesting & relevant. #CRISPR #BioTech #FinTwit #Genomics #GeneEditing ­čžÁ CRISPR Therapeutics, a biopharmaceutical company focused on
2/IMO the most significant corporate event in Q4 was $CRSP announcement that regulatory Exa-cel submissions of both #SickleCell & #BetaThalassemia validated in the #EU & #UK & that the @US_FDA BLA submission is on track by the end of Q1 ÔÇś23 - possibly reaching the #markets in ÔÇś23 Regulatory submissions complete for exagamglogene autotemcel
3/Exa-cel/CTX001 - the key program in $CRSP portfolio, is an #autologous Ex-Vivo #CRISPR/#Cas9 #GeneEditing therapy aimed for patients suffering from #TDT or severe #SCD. The latest readout for both programs was phenomenal with 42/44 TDT & 31/31(!) demonstrated remarkable results 3/Exa-cel - formally known as CTX001 and the key program in
Read 17 tweets
AB'nin Rus Gaz─▒ Mahrumiyeti ve T├╝rklere Mecburiyeti

Bug├╝n do─čalgaz devi Rus #Gazprom ┼čirketi,
Ursula von der Leyen'in ba┼č─▒nda bulundu─ču AB heyetinin Bak├╝'de do─čalgaz anla┼čmas─▒na imza att─▒─č─▒ s─▒rada Almanya'ya yapt─▒─č─▒ do─čalgaz ak─▒┼č─▒n─▒ durdurmas─▒ tesad├╝fi de─čil.­čĹç
Avrupa'n─▒n bug├╝nlerde 'G├╝ney gaz ve petrol koridorunun kilit orta─č─▒' olarak nitelendirdi─či #Azerbaycan, Rusya'n─▒n do─čalgaz ├╝retim hacminde olmasa da Avrupa'daki sanayi ├žarklar─▒n─▒n durmas─▒n─▒ ├Ânleyebilecek en h─▒zl─▒ se├ženek. G├╝ney gaz koridoru ise do─črudan T├╝rkiye'dir. ­čĹç
#Ortado─ču gaz ve petrol tedarik a─č─▒n─▒n vazge├žilmez ├╝lkesi T├╝rkiye, en az maliyetle en g├╝venli gaz─▒ Avrupa'ya ula┼čt─▒rmas─▒ bak─▒m─▒ndan Bat─▒ i├žin ├Ânemli bir ├╝lkeydi. Art─▒k sand─▒─č─▒m─▒zdan da ├Ânemli olmak ├╝zere...­čĹç
Read 15 tweets
This is about Alpha Zero.

But I think it is basically how human impulse control works. If a person chronically makes "bad" short-term-oriented choices, it may very well be because they _correctly_ don't depend on themselves to be able to execute on a long term strategy.
It's a lot less attractive to be "disciplined" and "responsible" and "prudent" if you're going to fuck it up somehow before you get the payoff.

You might as well seize some pleasure now, even if it is "self destructive" or reckless.
If you're likely to fail anyway, there's less use in focusing on your studies. Might as well party.

If you're going to misinvest your savings, or break open the piggy bank to buy some random thing down the line, you might as well spend the money now.
Read 18 tweets

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