Discover and read the best of Twitter Threads about #TIR
Most recents (15)
1a) Welcome to a 🆕#accredited #tweetorial on the importance of time in range #TIR in #diabetes . . . with additional emphases on #primarycare and on practice in 🇨🇦.
#FOAMed #endotwitter #MedEd @MedTweetorials #nephtwitter #cardiotwitter
#FOAMed #endotwitter #MedEd @MedTweetorials #nephtwitter #cardiotwitter
1b) Hence we welcome2⃣ expert faculty from Canada: Ilana Halperin @ilanajhalperin, academic endocrinologist at @Sunnybrook and @uoftmedicine, and Noah Ivers @NoahIvers, #familydoc & researcher at Women's College Hospital @UofT 
2) Earn 0.75hr 🆓CE/#CME by following this🧵! This program is supported by an unrestricted educational grant from Sanofi Canada and is intended for #HCPs. Statement of accreditation & faculty disclosures at cardiometabolic-ce.com/disclosures/.
And so we begin . . .
And so we begin . . .
🧵How can #HCP assist people who chose to use #DYIAID?
The @OPENDiabetesEU ⤵️
▶️ Katarina Braune is a co-founder
▶️ Patient-led
▶️ 2/3 of the international team live w/#T1D
▶️ #OpenSource #AID data
#ISPAD2022 #dedoc°voices #wearenotwaiting @dedocORG @ispad_org 1/n
The @OPENDiabetesEU ⤵️
▶️ Katarina Braune is a co-founder
▶️ Patient-led
▶️ 2/3 of the international team live w/#T1D
▶️ #OpenSource #AID data
#ISPAD2022 #dedoc°voices #wearenotwaiting @dedocORG @ispad_org 1/n
How can #HCP assist people who chose to use #DYIAID?
#wearenotwaiting movement ⤵️
Because DIY #ClosedLoop systems have been so life-changing for them and their kids, they decided to make it available for all.
#ISPAD2022 #dedoc°voices #payitforward @dedocORG @ispad_org 2/n
#wearenotwaiting movement ⤵️
Because DIY #ClosedLoop systems have been so life-changing for them and their kids, they decided to make it available for all.
#ISPAD2022 #dedoc°voices #payitforward @dedocORG @ispad_org 2/n
How can #HCP assist people who chose to use #DYIAID?
International consensus statement on #OpenSource automated insulin delivery ⤵️
✅ Published in @TheLancetEndo on Nov 13 2021
▶️ thelancet.com/journals/landi…
#ISPAD2022 #dedoc°voices #payitforward @dedocORG @ispad_org 3/n
International consensus statement on #OpenSource automated insulin delivery ⤵️
✅ Published in @TheLancetEndo on Nov 13 2021
▶️ thelancet.com/journals/landi…
#ISPAD2022 #dedoc°voices #payitforward @dedocORG @ispad_org 3/n
🧵#AI based decision support systems:
✅ Improves clinical outcomes
✅ Higher access to care
✅ Provides precision medicine
-Revital Nimri
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #diabetesadvocacy #patientvoice #payitforward @dedocORG @ispad_org 1/n
✅ Improves clinical outcomes
✅ Higher access to care
✅ Provides precision medicine
-Revital Nimri
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #diabetesadvocacy #patientvoice #payitforward @dedocORG @ispad_org 1/n
#AI based decision support systems:
'Is the quality of care improving?
No, it isn't.
We must do better.'
-Revital Nimri
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #diabetesadvocacy #patientvoice #payitforward @dedocORG @ispad_org 2/n
'Is the quality of care improving?
No, it isn't.
We must do better.'
-Revital Nimri
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #diabetesadvocacy #patientvoice #payitforward @dedocORG @ispad_org 2/n
#AI based decision support systems:
✅ Self-management tools
✅ Diagnosis, screening, prevention of #diabetes
✅ Prediction tools
✅ Clinical management
-Revital Nimri
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 3/n
✅ Self-management tools
✅ Diagnosis, screening, prevention of #diabetes
✅ Prediction tools
✅ Clinical management
-Revital Nimri
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 3/n
🧵 Sleep quality and patterns in children with #T1D:
Sleep deprivation can ⬆️ mental health issues like depression, a greater emotional response & difficulty to control emotions.
-Alice Gregory
#ISPAD #ISPAD2022 #dedoc°voices #patientvoice #payitforward @dedocORG @ispad_org 1/n
Sleep deprivation can ⬆️ mental health issues like depression, a greater emotional response & difficulty to control emotions.
-Alice Gregory
#ISPAD #ISPAD2022 #dedoc°voices #patientvoice #payitforward @dedocORG @ispad_org 1/n
Sleep quality and patterns in children with #T1D:
T1D is a 24/7 monitoring. It never stops at night.
Kids w/T1D have shorter sleep patterns and have poorer sleep quality.
-Alice Gregory
#ISPAD #ISPAD2022 #dedoc°voices #patientvoice #payitforward @dedocORG @ispad_org 2/n
T1D is a 24/7 monitoring. It never stops at night.
Kids w/T1D have shorter sleep patterns and have poorer sleep quality.
-Alice Gregory
#ISPAD #ISPAD2022 #dedoc°voices #patientvoice #payitforward @dedocORG @ispad_org 2/n
Sleep quality and patterns in children with #T1D:
Kids w/T1D have a different sleep architecture with less time in deep sleep whereas sleep is vitally important and particularly for kids w/T1D.
-A. Gregory
#ISPAD #ISPAD2022 #dedoc°voices #payitforward @dedocORG @ispad_org 3/n
Kids w/T1D have a different sleep architecture with less time in deep sleep whereas sleep is vitally important and particularly for kids w/T1D.
-A. Gregory
#ISPAD #ISPAD2022 #dedoc°voices #payitforward @dedocORG @ispad_org 3/n
🧵Microbiota: can they prevent #TID?
Incidence of T1D is rising particularly in the young.
Environmental factors could drive this pattern observed across the globe.
-N. Hanssen
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 1/n
Incidence of T1D is rising particularly in the young.
Environmental factors could drive this pattern observed across the globe.
-N. Hanssen
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 1/n
Microbiota: can they prevent #TID?
+ rapid destruction of #BetaCells in kids than adults.
#PwD with residual beta cells have higher #TIR.
-N. Hanssen
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 2/n
+ rapid destruction of #BetaCells in kids than adults.
#PwD with residual beta cells have higher #TIR.
-N. Hanssen
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 2/n
Microbiota: can they prevent #TID?
Poor discrimination between self/not self [#autoimmunity] happens with loss of gut microbiome.
-N. Hanssen
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 3/n
Poor discrimination between self/not self [#autoimmunity] happens with loss of gut microbiome.
-N. Hanssen
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 3/n
The last mile for #T1D cure:
'I believe that cell therapy can be the T1D cure. We've had landmark results in the last 2y.
-L. Piemonti
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs
#diabetesadvocacy #patientvoice #payitforward @dedocORG @ispad_org 1/n
'I believe that cell therapy can be the T1D cure. We've had landmark results in the last 2y.
-L. Piemonti
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs
#diabetesadvocacy #patientvoice #payitforward @dedocORG @ispad_org 1/n
The last mile for #T1D cure:
'We know now that #BetaCell replacement can cure T1D. This is the #BG profile of someone who used to live with #diabetes 1y 1/2 ago.'
-L. Piemonti
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 2/n
'We know now that #BetaCell replacement can cure T1D. This is the #BG profile of someone who used to live with #diabetes 1y 1/2 ago.'
-L. Piemonti
#ISPAD #ISPAD2022 #dedoc°voices #NothingAboutUsWithoutUs #payitforward @dedocORG @ispad_org 2/n
The last mile for #T1D cure:
'We started #BetaCell in Milan replacement in 1989. Had to wait for 30y for this procedure to be recognised.'
-L. Piemonti
Can you imagine living without the mental load & physical burden of #diabetes?
#ISPAD2022 #dedoc° @dedocORG @ispad_org 3/n
'We started #BetaCell in Milan replacement in 1989. Had to wait for 30y for this procedure to be recognised.'
-L. Piemonti
Can you imagine living without the mental load & physical burden of #diabetes?
#ISPAD2022 #dedoc° @dedocORG @ispad_org 3/n
Digitalization in Diabetes Education and Care:
'We know that autoimmunity starts way before #T1D diagnosis - if screened. We learnt that #cpeptide might not be relevant thanks to models'
-Dr A. Galderisi
#ISPAD #ISPAD2022 #dedoc°voices
#patientvoice #payitforward @dedocORG 1/n
'We know that autoimmunity starts way before #T1D diagnosis - if screened. We learnt that #cpeptide might not be relevant thanks to models'
-Dr A. Galderisi
#ISPAD #ISPAD2022 #dedoc°voices
#patientvoice #payitforward @dedocORG 1/n
Digitalization in Diabetes Education and Care:
'We can find heterogeneity in #T1D even before diagnosis. Important to individualise treatment.'-Dr A. Galderisi
Yes, every #PwD has their own #diabetes.
#ISPAD #ISPAD2022 #dedoc°voices
#nothingaboutuswithoutus @dedocORG 2/n
'We can find heterogeneity in #T1D even before diagnosis. Important to individualise treatment.'-Dr A. Galderisi
Yes, every #PwD has their own #diabetes.
#ISPAD #ISPAD2022 #dedoc°voices
#nothingaboutuswithoutus @dedocORG 2/n
Digitalization in #diabetes Education and Care:
'#TIR and #BG daily variability matter though we still look at the big picture. #AI can help us understand further.'
-Dr A. Galderisi
#ISPAD #ISPAD2022 #dedoc°voices
#patientvoice #payitforward @dedocORG 3/n
'#TIR and #BG daily variability matter though we still look at the big picture. #AI can help us understand further.'
-Dr A. Galderisi
#ISPAD #ISPAD2022 #dedoc°voices
#patientvoice #payitforward @dedocORG 3/n
Betting for the next best thing in digital #diabetes technology:
'#AID systems & algorithms are very effective.
Unfortunately, they are used by a minority of ppl who cld benefit from them.'
-Steven Russell
#EASD2022 #dedoc°voices #nothingaboutuswithoutus @dedocORG 1/n
'#AID systems & algorithms are very effective.
Unfortunately, they are used by a minority of ppl who cld benefit from them.'
-Steven Russell
#EASD2022 #dedoc°voices #nothingaboutuswithoutus @dedocORG 1/n
Betting for the next best thing in digital #diabetes technology:
'In addition to the challenges of getting hybrid #AID systems, they still require setups. They still require the user to #carbcount for meals & initiate correction boluses.'
-Steven Russell
#EASD2022 #dedoc 2/n
'In addition to the challenges of getting hybrid #AID systems, they still require setups. They still require the user to #carbcount for meals & initiate correction boluses.'
-Steven Russell
#EASD2022 #dedoc 2/n
Betting for the next best thing in digital #diabetes technology:
'The #IletBionicPancreas pivotal trial results will be published by end Sept.' -Steven Russell
✅ Only setup needed: @PwD's weight
✅ No #carbcounting
✅ Fully automated
#EASD2022 #dedoc°voices #BetaBionics 3/n
'The #IletBionicPancreas pivotal trial results will be published by end Sept.' -Steven Russell
✅ Only setup needed: @PwD's weight
✅ No #carbcounting
✅ Fully automated
#EASD2022 #dedoc°voices #BetaBionics 3/n
Are we becoming robots? #AID systems for everyone with #T1D:
'#CGM is the Archimedean point of #diabetes technology. This is when the idea of closing the loop really emerged.'
-Moshe Phillip
#EASD2022 #dedoc°voices #nothingaboutuswithoutus @EASDnews @dedocORG 1/n
'#CGM is the Archimedean point of #diabetes technology. This is when the idea of closing the loop really emerged.'
-Moshe Phillip
#EASD2022 #dedoc°voices #nothingaboutuswithoutus @EASDnews @dedocORG 1/n
[#thread] Déception à la lecture de la newsletter du @CeeD_Diabete qui paraphrase l’ANSM sur les #BouclesFermées DIY. Avec +5 ans d’expérience utilisateurs les développeurs du #DIY ont ouvert la voie aux boucles commerciales 🚀
▶️ ceed-diabete.org/blog/alerte-su…
#DIYAPS #DT1
▶️ ceed-diabete.org/blog/alerte-su…
#DIYAPS #DT1
Les #BouclesFermées commerciales ne sont pas encore disponibles en France, et le seront à un public restreint. Elles le sont depuis 2 ans dans d’autres pays. Les #DT1 ne peuvent plus attendre et construisent leur propre boucle avec du matériel marqué CE.
#WeAreNotWaiting
#WeAreNotWaiting
#ControlIQ Tandem T:slim #closedloop's aim at improving #TIR. To activate Control IQ, are required:
▶️ current weight
▶️ total daily #Insulin
▶️ carb ratio
▶️ ISF
▶️ correction factors
▶️ meal bolus still required
#dedoc° #dedocvoices #EASD2020 @EASDnews #NothingAboutUsWithoutUs
▶️ current weight
▶️ total daily #Insulin
▶️ carb ratio
▶️ ISF
▶️ correction factors
▶️ meal bolus still required
#dedoc° #dedocvoices #EASD2020 @EASDnews #NothingAboutUsWithoutUs
36 wk-trial #ControlIQ in teens and adults in 2019:
▶️ #TIR +11% from 61 to 71%
▶️ major #BG improvement at night 2 to 8am
▶️ average #A1c 7% (#PwD witth A1c >6.5% improved too)
▶️ less #hypos
- Dr Marc Breton, University of Virginia
#dedoc° #dedocvoices #EASD2020 @EASDnews
▶️ #TIR +11% from 61 to 71%
▶️ major #BG improvement at night 2 to 8am
▶️ average #A1c 7% (#PwD witth A1c >6.5% improved too)
▶️ less #hypos
- Dr Marc Breton, University of Virginia
#dedoc° #dedocvoices #EASD2020 @EASDnews
#ControlIQ in real life for 6086 users, average age 42yo, for 6 months:
▶️ #TIR 74.9% for 180 days
▶️ consistent improvement in #BG control
- Dr Marc Breton, University of Virginia
#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs
▶️ #TIR 74.9% for 180 days
▶️ consistent improvement in #BG control
- Dr Marc Breton, University of Virginia
#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs
Evaluation of the #OmnipodHorizon™ automated glucose control system in children with type 1 diabetes:
* Connected to #DexcomG6
* Algorithm built into the pod
* Phone controller or PDM
- Dr Gregory Forlenza
#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs
* Connected to #DexcomG6
* Algorithm built into the pod
* Phone controller or PDM
- Dr Gregory Forlenza
#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews #NothingAboutUsWithoutUs
Evaluation of the #OmnipodHorizon™ in children with #type1diabetes: usual drop in #TIR during the winter holidays. Study started during a challenging time - Dr Gregory Forlenza
#dedoc° #dedocvoices #EASD2020 #EASD
@EASDnews #NothingAboutUsWithoutUs
#dedoc° #dedocvoices #EASD2020 #EASD
@EASDnews #NothingAboutUsWithoutUs
Evaluation of the #OmnipodHorizon™ in children with #type1diabetes:
* reduced #BG variability
* #Hypo reduction
* 59% users chose the 110mg target (free choice)
- Dr Gregory Forlenza
#dedoc° #dedocvoices #EASD2020 #EASD
@EASDnews #NothingAboutUsWithoutUs
* reduced #BG variability
* #Hypo reduction
* 59% users chose the 110mg target (free choice)
- Dr Gregory Forlenza
#dedoc° #dedocvoices #EASD2020 #EASD
@EASDnews #NothingAboutUsWithoutUs
New strategy to treat #T1D: Simplici-T1 trail ⤵️
"subcutaneous #insulin is not enough" - Dr Carmen Valcare, on the activation of #glucokinase by #TTP399 improving #BG management.
Results: ⬇️ #TIR, #BG control, and #A1c
#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews
"subcutaneous #insulin is not enough" - Dr Carmen Valcare, on the activation of #glucokinase by #TTP399 improving #BG management.
Results: ⬇️ #TIR, #BG control, and #A1c
#dedoc° #dedocvoices #EASD2020 #EASD @EASDnews
Nouvelle stratégie pour traiter le #DT1 : Simplici-T1
"L'insuline sous-cutanée n'est pas suffisante" - Dr Carmen Valcare, sur l'activation de la #glucokinase par le #TTP399 améliorant la gestion de la #BG
Résultats : ⬇️#TIR, #glycémie et #Hba1c
#dedoc° #dedocvoices #EASD
"L'insuline sous-cutanée n'est pas suffisante" - Dr Carmen Valcare, sur l'activation de la #glucokinase par le #TTP399 améliorant la gestion de la #BG
Résultats : ⬇️#TIR, #glycémie et #Hba1c
#dedoc° #dedocvoices #EASD
La #TIR (Tasa Interna de Retorno) en escenarios de Default
Como sabemos, la TIR es la medida mas utilizada para la medición del rendimiento de los Bonos.
Sin embargo, hay casos donde no puede calcularse directamente contra el flujo de fondos del Prospecto del bono.
Como sabemos, la TIR es la medida mas utilizada para la medición del rendimiento de los Bonos.
Sin embargo, hay casos donde no puede calcularse directamente contra el flujo de fondos del Prospecto del bono.
Uno de estos casos es el que estamos viviendo actualmente: el #Default.
El mercado opera los bonos asumiendo que:
1. No se pagará el flujo de fondo original
2. Habrá una negociación por #Canje de deuda, que demorará algunos años
3 Se Sufrirá un porcentaje de #Quita de Capital
El mercado opera los bonos asumiendo que:
1. No se pagará el flujo de fondo original
2. Habrá una negociación por #Canje de deuda, que demorará algunos años
3 Se Sufrirá un porcentaje de #Quita de Capital
En este caso, usar la TIR como medida de rentabilidad es un ejercicio matemático INGENUO, ya que pasa a ser una medida FICTICIA.
Entonces, ¿qué hacemos?
Principalmente dejar de medir con la TIR
Entonces, ¿qué hacemos?
Principalmente dejar de medir con la TIR
L'esperto di #legambiente #Balotta e l'#ingegnere #Camomilla spiegano perché la colpa del disastro #PontiGenova #ponteMorandi é una precisa responsabilità del gestore #AutostradeperlItalia dei #Benetton
La colpa per mancata e insufficiente #manutenzione di #AutostradeperlItalia dei #Benetton é testimoniata dai dipendenti #Amiu #Genova #PonteMorandi #ponteGenova cdt.ch/mondo/cronaca/…
Smontate le #fakenews sulla #convenzione e sulla #revoca della #concessione ad #AutostradeperlItalia #PonteMorandi #ponteGenova #Genova @steal61 ilcappellopensatore.it/2018/08/revoca…
