Discover and read the best of Twitter Threads about #TRIALISTS
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1/7🔥ATTENTION #TRIALISTS
#tweetorial on our #openaccess paper @BMJMedicine
👉Trials of new medicines often include younger, healthier people than in general population
👉There may be concern that older people with multiple medical conditions may be less able to complete #trials
#tweetorial on our #openaccess paper @BMJMedicine
👉Trials of new medicines often include younger, healthier people than in general population
👉There may be concern that older people with multiple medical conditions may be less able to complete #trials
2/7
👉We looked at individual participant-level data from 92 trials of 20 medical conditions testing 17 different drug classes
👉We assessed whether age, sex and number of medical conditions was associated with attrition (dropout) from these trials
👉We looked at individual participant-level data from 92 trials of 20 medical conditions testing 17 different drug classes
👉We assessed whether age, sex and number of medical conditions was associated with attrition (dropout) from these trials
3/7
The *bad* news 😬
Individuals with multimorbidity are less likely to complete participation in clinical trials
The *good* news 😅
The effect is modest (and consistent across medical conditions and drug classes)
The *bad* news 😬
Individuals with multimorbidity are less likely to complete participation in clinical trials
The *good* news 😅
The effect is modest (and consistent across medical conditions and drug classes)
