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Our preprint about reinfection by the P.1 SARS-CoV-2 lineage in repeat blood donors in Manaus is now out [not peer-reviewed] 🧪🦠🥼🌎
▶️Check it out at: medrxiv.org/content/10.110….
▶️Short thread on key findings🧵 1/10
▶️Check it out at: medrxiv.org/content/10.110….
▶️Short thread on key findings🧵 1/10
It is challenging to estimate the reinfection rate since most reinfected individuals are likely not tested, and/or oligo or asymptomatic. Yet, reinfection has been postulated to explain at least in part the 2nd wave of COVID-19 in Manaus (see bit.ly/3hyjVWk). 2/10
To address this, we tested serial samples from unvaccinated repeat blood donors from Manaus w a seroprevalence assay that wanes during convalescence. We assumed that reinfections induce a boosting ↗️ in antibody (Ab) levels, leading to V-shaped time series of Ab reactivity. 3/10
