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Thrilled to see this one published in @JAMApsych. Here's a short thread discussing our findings on neurobiological #biomarkers of #depression. jamanetwork.com/journals/jamap…
In a large, bi-centric study (#FOR2107) on depression (n=1809), we quantified the univariate neurobiological differences between healthy subjects and patients with major depression across a number of MRI modalities (#sMRI, task and rest #fMRI, #DTI).
We show that the univariate difference between the two groups is remarkably small for all modalities, all explaining less than 2% of variance.
