Discover and read the best of Twitter Threads about #UroSoMe
Most recents (19)
In this #UrologyJournalClub we discuss and summarize the Belzitufan Phase 2 trial for renal masses in patients with Von Hippel-Lindau (VHL) disease published @NEJM which led to the approval of Welireg.
🔗 pubmed.ncbi.nlm.nih.gov/34818478/
💾urologiabe.files.wordpress.com/2021/11/urolog…
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@VPrasadMDMPH
🔗 pubmed.ncbi.nlm.nih.gov/34818478/
💾urologiabe.files.wordpress.com/2021/11/urolog…
1/
@VPrasadMDMPH
📃 phase 2, single arm, open label
N=61
Pts with VHL and renal masses (assumed to be renal cell carcinoma, biopsy not required).
Most pts had other VHL-related tumors simultaneously but these were not considered for inclusion or exclusion criteria but measured either way.
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N=61
Pts with VHL and renal masses (assumed to be renal cell carcinoma, biopsy not required).
Most pts had other VHL-related tumors simultaneously but these were not considered for inclusion or exclusion criteria but measured either way.
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This study found an objective response rate of 49% (quite impressive for a drug in an orphan disease), another 49% of patients showed stable disease and only 3 patients had progression.
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Our paper on #Manels in Urology just published @EUplatinum. For those who do not believe #Manel is a major problem in urology, I sincerely encourage you to read this. (1/n) Free download link: authors.elsevier.com/a/1dBNY14kplnU…
In this study, we reviewed one year of conferences/webinars organized by major urological associations and societies. We investigated the overall proportion of #Manels, which was defined as the composition of all-male chairs/moderators plus all-male speakers. (2/n)
Among the 285 meeting sessions being included, 63.5% of them were #Manels! The mean percentages of male faculty were mostly >85% across different associations/societies, and >85% across the different subspecialties. (3/n)
In last month’s issue of #SIUJ, @JessicaDeLong23 and @RamonVirasoro discuss the development of a GURS fellowship and training program in the Caribbean bit.ly/3tliRIb #OpenAccess #urology #urosome
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With over 5 billion people lacking access to adequate surgical and anesthesia care across the globe, the global health community is focusing on reducing these health inequalities by improving access and overall outcomes.
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During annual mission trips to Dominican Republic (DR), the authors recognized a need for more Urological Reconstructive Surgery trained physicians within the community. This need inspired the creation of a GURS in the DR.
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📚 Based on Urology by Campbell
#uroquiz #endourology #urosome
@MSGONZALEZURO @ResidentesAEU @sbinhamrii @oangerri @Urologeman @CheatUrology @drkemalsarica @FCFigueiredo @migokce
🚩The most significant factor for #stone formation in pts w/ #struvite calculi is:
#uroquiz #endourology #urosome
@MSGONZALEZURO @ResidentesAEU @sbinhamrii @oangerri @Urologeman @CheatUrology @drkemalsarica @FCFigueiredo @migokce
🚩The most significant factor for #stone formation in pts w/ #struvite calculi is:
✅ ℝ𝕖𝕔𝕦𝕣𝕣𝕖𝕟𝕥 𝕌𝕋𝕀𝕤
🔹Struvite stone formation typically occurs in pts w/ recurrent UTI and retained urine
🔹Predisposing factors include:
🔸urinary tract obstruction
🔸chronic indwelling catheter
🔸urinary diversion
🔸neurogenic voiding dysfn
📸 @VelezNephHepato
🔹Struvite stone formation typically occurs in pts w/ recurrent UTI and retained urine
🔹Predisposing factors include:
🔸urinary tract obstruction
🔸chronic indwelling catheter
🔸urinary diversion
🔸neurogenic voiding dysfn
📸 @VelezNephHepato
🔹Most commonly, #staghorn stones are composed of a mixture of struvite (magnesium ammonium phosphate) and calcium carbonate apatite.
🔹#Struvite calculi are typically referred to as “infection stones” because of their strong association w/ UTI.
📸 Radiopaedia.org
🔹#Struvite calculi are typically referred to as “infection stones” because of their strong association w/ UTI.
📸 Radiopaedia.org
@LiangGQu, Vaisnavi Thirugnanasundralingam, @damien_bolton, @UroOncMD & @lawrentschuk reviewed the role of tissue-based immunohistochemical markers for diagnosis and classification of #RCC in this 1st edition of #SIUJ!
#OpenAccess #UroSoMe
siuj.org/index.php/siuj…
1/n
#OpenAccess #UroSoMe
siuj.org/index.php/siuj…
1/n
Hey all, time for another Urology tweetorial on Fournier gangrene (FG). We will briefly cover the history, epidemiology, pathophysiology, and management. Special thanks in advance to my wonderful mentor @RamonVirasoro! #UroSoMe
The first documented case of FG is from 800 BC by an Arab physician Avicenna who practiced in Uzbekistan. He identified perineal gangrene as a complication of transperineal bladder stone removals (impressive that they were doing these).
FG first documented in modern history was by Dr. Baurienne(1764) in France in which he described a boy gored by an ox in the scrotum.
It is my great pleasure to guest edit this Special Issue on #AEEP!! Thank you all contributors in making this happen. #AEEP - It is a Quest for the Best!! #UroSoMe (1/n) onlinelibrary.wiley.com/toc/14390272/2…
At the beginning of MS3 year I felt, very strongly, I needed to actively be doing things to learn. I underestimated the value of quiet, observation. As I’ve transitioned from a MS3 to a MS4, I now appreciate it as one of my greatest learning opportunities. Today, I was 1/
reminded of why. For the first time I witnessed a frustrated pt allege a physician entered the field solely for money. We arrived to this point with the use of the word, “supposedly”. The pt felt dismissed, not cared for and that they were being viewed as incompetent in their 2/
ability to convey their PMHx. Word choice and syntax are exceptionally powerful tools. As a kid I was taught, “Sticks and stones may break my bones, but words will never hurt me.” That’s not true, though. Words can be hurtful and hurt people try to hurt people. Words can heal 3/
I read "Day 1 - A world made for men." by @emmabgo.
Excellent piece, that made me recognize that I inhabit a subspecialized work world that is specifically designed for men.
A thread:
nytimes.com/programs/women…
Excellent piece, that made me recognize that I inhabit a subspecialized work world that is specifically designed for men.
A thread:
nytimes.com/programs/women…
Every time I need to put the cover on the sterile light-handles, I scan the room: “Hi, tall friend! Can you help me?”.
For those of us who work in the operating room (OR), it is immediately evident that the room was designed with a much taller person in mind… a man.
For those of us who work in the operating room (OR), it is immediately evident that the room was designed with a much taller person in mind… a man.
During five years of residency, I thought it was me, that I was too short or my hands were too small. I stood on step stools, and still experienced significant height mismatching.
Oftentimes, I would have hand pain and neck pain for days after a long surgery.
Oftentimes, I would have hand pain and neck pain for days after a long surgery.
Alright #MedTwitter you asked, therefore you shall receive. Find below the results of me sifting through all of the replies and quoted retweets to the HP House poll that were visible to me.
Total N=1282!
Total N=1282!
First, we'll do each HP Houses.
Note: If a House had no self proclaimed members of a specific specialty, that specialty was not included in its graph.
Note: If a House had no self proclaimed members of a specific specialty, that specialty was not included in its graph.
GRYFFINDOR
💡A few thoughts about the recently published PROfound trial “Olaparib for Metastatic Castration-Resistant Prostate Cancer” @ NEJM.
I decided to give a shot at critical lecture.
The first thing that draw my attention was the inclusion criteria.
#UroSoMe @VPrasadMDMPH
1/8
I decided to give a shot at critical lecture.
The first thing that draw my attention was the inclusion criteria.
#UroSoMe @VPrasadMDMPH
1/8
"men with confirmed M1 castration-resistant prostate cancer (CRPC) whose disease had progressed during treatment with enza or abi, administered for M1 or M0 CRPC or M1 hormone-sensitive prostate cancer. Previous taxane chemotherapy was allowed.”
Now look at control arm 👀
2/8
Now look at control arm 👀
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So.. to be included u had to progress to the control arm, that way, chances of doing well, correct me if I’m wrong but are pretty low.
One may argue that you can give it either way, but to the best of my knowledge this is NOT standard of care.
3/8
One may argue that you can give it either way, but to the best of my knowledge this is NOT standard of care.
3/8
RIRS and Pressure
1/ Hi everyone! Warning - not a "COVID" tweet
I'd like to present a little summary on intrarenal pressure (IRP) during RIRS
1 cmH2O = 0.73 mmHg
IRP should be kept lower than 30 cm H2O
Lowest irrigation flow (IF) to keep a clear vision is 21 ml/min
1/ Hi everyone! Warning - not a "COVID" tweet
I'd like to present a little summary on intrarenal pressure (IRP) during RIRS
1 cmH2O = 0.73 mmHg
IRP should be kept lower than 30 cm H2O
Lowest irrigation flow (IF) to keep a clear vision is 21 ml/min
2/
With no Ureteral Access Sheath (UAS) gravity irrigation pressure of 50, 100, and 200 cm H2O will lead to 15, 30, and 55 cm H2O of IRP with IF of 23, 47 and 80 mL/min correspondingly
The maximal IRP during manual irrigation can reach 598.4 cm H2O
With no Ureteral Access Sheath (UAS) gravity irrigation pressure of 50, 100, and 200 cm H2O will lead to 15, 30, and 55 cm H2O of IRP with IF of 23, 47 and 80 mL/min correspondingly
The maximal IRP during manual irrigation can reach 598.4 cm H2O
3/
With gravity IP of 100 cm H2O with a 242 μm laser fiber in the working channel and no outflow resistance IF was 14 to 15 mL/minute
Difference between UAS and outer diameter of scope should be no less than 3 Fr
IRPs remain lower than 30 cmH2O if a UAS bigger than 10/12 F
With gravity IP of 100 cm H2O with a 242 μm laser fiber in the working channel and no outflow resistance IF was 14 to 15 mL/minute
Difference between UAS and outer diameter of scope should be no less than 3 Fr
IRPs remain lower than 30 cmH2O if a UAS bigger than 10/12 F
May I take this opportunity to ask... Has Covid-19 affected your hospital, clinic, operations, clinical practice so far? #UroSoMe
In Hong Kong, our urology clinic has a default rate of about 30%, operative list cut by >50%... #UroSoMe
What is the Impact of Covid-19 on Urological Service? I must confess, this is not a short survey. BUT by spending 10min of your time (Promise), we can learn so much more from each other. Please help to fill in the survey! (On behalf of the #UroSoMe group) surveymonkey.co.uk/r/8KJNSDH
Coronavirus has become a frequently discussed issue within the urological community.. I wish to share this article with you all, a @NEJM paper written by the China Expert Group for Covid-19, and co-authored by Prof. David Hui from @CUHKMedicine. #UroSoMe (1/n)
For easy reference, I will try to write down the summary in bullet points (2/n)
Baseline data
- 1099 patients with Covid-19 from 552 hospitals and 30 provinces in China.
- Median age was 47 years
- 58.1% were male
- 1.9% had direct contact with wildlife animals
#UroSoMe
Baseline data
- 1099 patients with Covid-19 from 552 hospitals and 30 provinces in China.
- Median age was 47 years
- 58.1% were male
- 1.9% had direct contact with wildlife animals
#UroSoMe
Presentation (3/n)
- 43.8% had fever upon admission, but 88.7% had fever during the whole hospitalization
- 67.8% had cough
- Only 3.8% had diarrhea
- Median incubation period was 4 days
#UroSoMe
- 43.8% had fever upon admission, but 88.7% had fever during the whole hospitalization
- 67.8% had cough
- Only 3.8% had diarrhea
- Median incubation period was 4 days
#UroSoMe
A question for all urologists... What is your prediction for the standard of care in the next 10 years? Anything related to urology - Please propose! #UroSoMe
What’s your view on focal therapy for prostate cancer? #UroSoMe
12 Tips for making great surgical videos (from my experience with judging @VattikutiRobotx KS video awards (A thread):
1. Good content is foremost - Eg: succinct explanation of anatomy, your unique contribution to technique, Complications (and how to avoid them), etc.
1. Good content is foremost - Eg: succinct explanation of anatomy, your unique contribution to technique, Complications (and how to avoid them), etc.
2. Choose and preserve highest resolution possible (play with recording and rendering settings).
3. Frequent camera cleans/focus (if needed) if you are planning to record a special case.
3. Frequent camera cleans/focus (if needed) if you are planning to record a special case.
4. Record EVERY case (you never know when you will find something interesting).
5. Keep it short (make best use of time, but it is not necessary to use up all those 8 minutes). NEVER exceed the allotted time.
5. Keep it short (make best use of time, but it is not necessary to use up all those 8 minutes). NEVER exceed the allotted time.
A myth can be defined as "a fictitious or imaginary person or thing". Are there any Myths in Urology / Urological Practice? Can you share with us? #UroSoMe
“Doctor, I have stopped drinking milk because I have calcium containing stones!” #UroSoMe
Eating oysters can improve erection. This is a myth being spread in Chinese I think.. #UroSoMe
1. Do you have interest in prostate cancer?
2. Do you want to learn how to read MRI prostate?
3. Do you want to have paired MRI images for learning purposes?
We have 50 study cases for you with histological feedback. Let me know if you are interested!
#UroSoMe
2. Do you want to learn how to read MRI prostate?
3. Do you want to have paired MRI images for learning purposes?
We have 50 study cases for you with histological feedback. Let me know if you are interested!
#UroSoMe
The responses were overwhelming - Sorry if I am not responding as quickly as I should have! #UroSoMe
Today is a big day for #UroSoMe and we wish to take this opportunity to recap what we have done in the past and we are planning to do in the future. This is an amazing story which would never be successful without your support. (1/n)
The idea of #UroSoMe came up in late 2018 and we gathered a group of urologists who are very committed to this. It is not easy to build up #UroSoMe, and it is even more difficult to sustain it. We share a common vision and that is the major reason that keeps #UroSoMe going..(2/n)
#UroSoMe stands for ‘Urology Social Media’. There is so much for us to learn from each other, and such interactions should never be bounded by physical or geographical restrictions. “The beginning of #UroSoMe” was posted @BJUIjournal blog site. (3/n) bjuinternational.com/bjui-blog/blog…
