Discover and read the best of Twitter Threads about #VitaminB12
Most recents (6)
Cerebral atrophy (brain shrinkage) in an infant: Sad story with a happy ending
1. 10-month old infant was brought by his parents with generalized weakness & lethargy for 4 months. His motor milestones had also slowed down. He was evaluated by a local pediatrician.
#MedTwitter
1. 10-month old infant was brought by his parents with generalized weakness & lethargy for 4 months. His motor milestones had also slowed down. He was evaluated by a local pediatrician.
#MedTwitter
2. Thyroid profile was normal. MRI brain showed severe, diffuse cerebral atrophy (generalized shrinkage of brain).
Anticipating a neurodegenerative disease, pediatrician referred the infant for a neurologist's opinion.
I took a detailed history and ordered for a blood test.
Anticipating a neurodegenerative disease, pediatrician referred the infant for a neurologist's opinion.
I took a detailed history and ordered for a blood test.
3. I reserved my opinion regarding prognosis, until the blood report came. I also did not want to send the infant for a series of investigations to rule out rare neurodegenerative diseases before seeing the blood test report.
Mother was a strict vegetarian, which gave the clue.
Mother was a strict vegetarian, which gave the clue.
Shaking of hands and burning feet in a middle aged person: look for this treatable cause
1. 56-yr old Mr K presented with shaking of hands for several months, and burning & tingling of feet for 2 weeks. He had been started on trihexyphenidyl for tremors by a neurologist.
1. 56-yr old Mr K presented with shaking of hands for several months, and burning & tingling of feet for 2 weeks. He had been started on trihexyphenidyl for tremors by a neurologist.
2. Clinical examination revealed action (postural) tremors. He had no slowness of moments, rigidity or balance issues.
Tremors were suggestive of essential tremors (ET). Burning feet was suggestive of sensory neuropathy. He had no numbness or weakness of feet.
#Medtwitter
Tremors were suggestive of essential tremors (ET). Burning feet was suggestive of sensory neuropathy. He had no numbness or weakness of feet.
#Medtwitter
3. Blood tests done earlier showed vitamin B12 deficiency. All meals consumed by Mr K (except 4 meals/month) were vegetarian.
NCV studies confirmed sensory neuropathy (damage to nerves of both feet).
Putting everything together, vitamin B12 deficiency is the most likely cause.
NCV studies confirmed sensory neuropathy (damage to nerves of both feet).
Putting everything together, vitamin B12 deficiency is the most likely cause.
Eigentlich dachte ich, dass zum Thema B12 genug gesagt und bereits alles bekannt ist. Die Drukos auf einen meiner jüngsten Tweets haben aber leider das Gegenteil belegt. Daher heute eine Folge meiner Serie zum Thema Vitamin B12. B12 ist bei der Synthese der DNA-Basen beteiligt
und somit für Zellwachstum und Zellteilung sowie geistige Entwicklung essentiell. Bei einem Mangel an B12 kommt es zu einem Mangel an aktiven Folat und in der Folge zu einer gestörten Bildung der roten Blutkörperchen (megaloblastäre Anämie) und einer zu Leitungsstörungen im
Nervensystem (funikuläre Myelose) sowie einer Schädigung der peripheren Nerven (Polyneuropathie). Außerdem können zerebrale Störungen mit Entwicklung einer Demenz auftreten, auch mit Depressionen wird B12-Mangel in Verbindung gebracht. Diese Schädigungen sind teils irreversibel.
Back in college, I was once appearing for a viva vôce of an economics related subject. The examiner asked us an out-of-syllabus question, "Why do you think the govt gives subsidies for poultry industry?" I will remain forever grateful to my 🧠 for bringing up the answer! Tiny🧵👇🏼
For reasons I still do not understand, my brain remembered something we are taught in primary school. Kwashiorkor is a disease caused by severe protein deficiency. Shamefully, children still die due to it in India. After getting reminded of kwashiorkor, I connected the dots.
I replied, "Kwashiorkor is still prevalent in India. By subsidizing the poultry industry, the govt is trying to increase supply of chicken. This will reduce prices of chicken thus making it more affordable to those who want to eat it. This can help reduce protein deficiency."
Why social media nutrition activism matters - a short thread ⬇️ A family member with a science degree was stunned to know about the sources of vitamin B12 .
I posted multiple stories about the animal sources of vitamin B12 on WhatsApp status. I love to use Canva & Adobe Express to make stories about cobalamin. I also explained that processed foods such as Kellogs cornflakes, Chocos, Horlicks, Boost, Marmite, etc have vitamin B-12.
So this gent met me in person the same day. Looking at my status on his phone, he asked, "Is this verified news?" I was wide-eyed. Here was an engineer who had biology till class 12. He had completely forgotten that we had learnt about the animal origin food sources of vitB12.
Excess of vitamin B12 may be hazardous
1. Vitamin #B12 deficiency is known to cause anemia, peripheral neuropathy, dementia, psychosis and skin pigmentation. Vitamin B12 supplementation is needed in them, however, #vitaminB12 excess may have adverse effects on health and life.
1. Vitamin #B12 deficiency is known to cause anemia, peripheral neuropathy, dementia, psychosis and skin pigmentation. Vitamin B12 supplementation is needed in them, however, #vitaminB12 excess may have adverse effects on health and life.
2. In a recent study, >5500 people (mean age 53 years) were followed up for 8.2 years.
Those with high plasma vitamin B12 concentration had 25% higher risk of all-cause death.
The mechanism of increased death is unknown.
#MedTwitter #nurtition #vitamin
Those with high plasma vitamin B12 concentration had 25% higher risk of all-cause death.
The mechanism of increased death is unknown.
#MedTwitter #nurtition #vitamin
3. Older age, high blood pressure, poorer kidney function, as well as increased concentrations of liver enzymes, were positively associated with higher plasma concentrations of vitamin B12. So, these groups should be more cautious while taking vitamin B12 supplementation.
