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Our dream comes true: the #WATERFALLtrial has been published in @NEJM Aggressive fluid resuscitation in acute pancreatitis is not safe & does not improve outcomes #GItwitter #SomosAEG @aegastro
What's behind this publication?
It all started 21 years ago
nejm.org/doi/full/10.10…
What's behind this publication?
It all started 21 years ago
nejm.org/doi/full/10.10…
2001, I started to attend patients with acute pancreatitis as a GI resident in @GVAsalualicante. Books and papers recommended aggressive fluid resuscitation. It was believed that many fluids increased pancreatic blood flow preventing pancreatic necrosis
But I asked to myself, what is aggressive fluid resuscitation, how much fluids, and which type of fluids? I looked for specific data, but all was vague. I asked in GI meetings, and the answers of experts were vague, no specific fluid rate, just generalities
