Discover and read the best of Twitter Threads about #WrapIPF
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1/n September Pulmonary Fibrosis controversy thread about #IPFandGERD preprint from Dr. Cosetta Minelli's group: Two tweets from really good people say "GERD Causes IPF" (@IPFdoc, @drcjar), and a 3rd (@LungDrE) says: "Not based on your data".
Who is right?
Who is right?
2/n I read the preprint (medrxiv.org/content/10.110…); A Mendelian Randomization (MR) study using summary stats of GERD GWAS gut.bmj.com/content/71/6/1… & IPF GWAS meta-analysis thorax.bmj.com/content/77/8/8….
Shows OR of 1.6 GERD➡️IPF & 0.99 IPF➡️GERD. So what do I think?
#IPFandGERD
Shows OR of 1.6 GERD➡️IPF & 0.99 IPF➡️GERD. So what do I think?
#IPFandGERD
3/n #IPFandGERD Paper obviously needs #PeerReview. But there is context.
As a non-expert, in reading Mendelian Randomization studies I go back to the superb Guide to reading Mendelian randomization studies from Prof Davey Smith & team. Especially that 👇🏼
bmj.com/content/362/bm…
As a non-expert, in reading Mendelian Randomization studies I go back to the superb Guide to reading Mendelian randomization studies from Prof Davey Smith & team. Especially that 👇🏼
bmj.com/content/362/bm…
