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In men, there is a small gland called prostate situated just below the bladder surrounding the proximal part of the urethra (tube which drains the bladder). Its job is to secrete seminal fluid that nourishes sperm.

In most men, it gets enlarged with age due to hormonal factors.
This increase in the size of the prostate with age is called Benign Prostate Enlargement or Hypertrophy (BPH).

It is distinct from prostate cancer & is not associated with increased incidence of cancer.

Sometimes it gets large enough to cause severe trouble requiring treatment
TURP: Trans Urethral Resection of prostate, where the urologist creates a tunnel for easy passage of urine is a common surgery today.

Newer modifications of the above are:

Plasma TURP: Different set of instruments & solution used to give same result with lesser complications.
Read 7 tweets
I came across lithium in 1991 during pharmacology semester 2nd MBBS.

I saw its use during my psychiatry postings. Its most common use was in mania & in bipolar disorder.

Lithium regulates certain neurotransmitters in the brain stabilizing the mood of the patient completely.
It prevents further episodes of mania/depression when patient is compliant & actually improves the patient's performance in all walks of life.

It is very well tolerated by most patients. However, regular monitoring of blood levels & follow up with the doctor is most important.
#Lithium is a very valuable tool in #psychiatry

It has saved more patients than all the help lines across the world have done.

We should thank Dr John Cade an Australian doctor who found the use of lithium & published it in 1949.

He used it on himself to check if it was safe.
Read 5 tweets

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