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Some more info on XBB.2.3. Aka #Acrux
➡️ XBB.2.3 has 4 defining mutations:
-Spike mutations: S:D253G & S:P521S
-ORF mutations: ORF1a:G2091S & ORF7a:A13V
-Beyond XBB.2, #Acrux XBB.2.3 has the Spike P521S & S486P mutations 1/
H/T: @T_Brautigan
➡️ XBB.2.3 has 4 defining mutations:
-Spike mutations: S:D253G & S:P521S
-ORF mutations: ORF1a:G2091S & ORF7a:A13V
-Beyond XBB.2, #Acrux XBB.2.3 has the Spike P521S & S486P mutations 1/
H/T: @T_Brautigan
➡️ Acrux XBB.2.3 was first spotted in India (Karnataka) & then in the USA—origin is somewhat unclear.
Here is the animated map by @Mike_Honey_ showing the spread of the XBB.2.3.* "Acrux" variant around the world. 2/
Here is the animated map by @Mike_Honey_ showing the spread of the XBB.2.3.* "Acrux" variant around the world. 2/
➡️ Singapore (26%) and India (22%) are still the hotspots.
Spain (11%) and Australia (8%) are also showing recent growth.
Spotted in many other countries including Japan, South Korea, China, the UK & the US. 3/
Spain (11%) and Australia (8%) are also showing recent growth.
Spotted in many other countries including Japan, South Korea, China, the UK & the US. 3/
Tracking #SARSCoV2 #Lineages - Globally
Top lineages -#20DayTrends (#G20):
XBB.1.5 (36.6%)⬇️
XBB.1.9.1 (11.5%)⬆️
EG.1 (4.7%)⬆️
XBB.1.16 (4.4%)⬆️
XBB.1.9.2 (3.1%)
XBB.2.3 (1.8%)
XBB.1.5.13 (1.6%)
XBB.1.16.1 (1.5%)
public.tableau.com/app/profile/ra…
Updated 04/29/23
Top lineages -#20DayTrends (#G20):
XBB.1.5 (36.6%)⬇️
XBB.1.9.1 (11.5%)⬆️
EG.1 (4.7%)⬆️
XBB.1.16 (4.4%)⬆️
XBB.1.9.2 (3.1%)
XBB.2.3 (1.8%)
XBB.1.5.13 (1.6%)
XBB.1.16.1 (1.5%)
public.tableau.com/app/profile/ra…
Updated 04/29/23
Granular details #Global #20DayTrends
This analysis includes all designated #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 04/09/2023 (14,137 sequences)
This analysis includes all designated #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 04/09/2023 (14,137 sequences)
#USA, #Austria, #France & #Canada have submitted a lion's share of sequences with sample collection dates on or after 04/09/2023 ...followed by #UnitedKingdom, #Australia, #Germany, #Sweden, #SouthKorea, #Singapore, #China, #Spain
It's likely that you'll be hearing more about another XBB descendant lineage, XBB.2.3*, alongside XBB.1.5 (Kraken), XBB.1.9.1 (Hyperion), and XBB.1.16 (Arcturus).
To aid communication, we're nicknaming XBB.2.3* "Acrux" (after the star en.wikipedia.org/wiki/Acrux).
To aid communication, we're nicknaming XBB.2.3* "Acrux" (after the star en.wikipedia.org/wiki/Acrux).
This is in keeping with the new nicknaming system that uses astronomical names and includes information about the lineage (starts with A-H = BA.2 lineage) and recombinant ancestry (has an R in the name = recombinant descendant).
whn.global/common-names-f…
whn.global/common-names-f…
It's easy to track variant info thanks to amazing tools by folks like @Mike_Honey_, @RajlabN, and @nextstrain.
public.tableau.com/app/profile/ra…
public.tableau.com/app/profile/ra…
