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2021 is off to a great start! I’m very excited to share my new study at @CellStemCell on using surface antigen-guided CRISPR screens to identify genes that regulate myeloid leukemia differentiation.
cell.com/cell-stem-cell…
cell.com/cell-stem-cell…
Here's my first tweetorial!
1. Here, we used two innovative genetic screen approaches, a cell surface-based genome-wide and single-cell (ECCITE-seq) CRISPR screens to identify regulators of AML differentiation.
1. Here, we used two innovative genetic screen approaches, a cell surface-based genome-wide and single-cell (ECCITE-seq) CRISPR screens to identify regulators of AML differentiation.
2. We focused our efforts on the mRNA decay factor, ZFP36L2 which demonstrated a strong dependency in human myeloid leukemia cell lines (@CancerDepMap).
