Discover and read the best of Twitter Threads about #airways

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#location location location: thrilled to share our work @CellCellPress! #interferons dictate #COVID19 severity! Specific #IFNs are produced along the #airways in response to #SARSCoV2 and drive protective or detrimental #transcriptional programs! 1/7 doi.org/10.1016/j.cell…
IFNs are driven by high #viral #loads, suggesting that viral recognition is only achieved when #SARSCoV2 reaches a certain threshold! Efficient induction of protective IFNs is preferentially achieved by younger patients, further explaining susceptibility of elders to #COVID19 2/7
#IFNL1 & #IFNL3 characterize mild illness & drive potent anti-#SARSCoV2 #ISGs in the upper #airways. Severe patients show #typeI IFN & #IFNL2 along the respiratory tract but lack ISGs, dampen cell proliferation programs associated to #repair and boost #apoptotic #p53 pathways 3/7
Read 7 tweets
Generally speaking #infrastructure is defined as the basic #physical systems of any #business, #region, or that of any #nation... including #transportation systems, #communication #networks, #sewage, #water supply & #electrical #grid systems. #BuildBackBetter #logistics #stimulus
Various types of #infrastructure #construction based projects typically drive the bulk of conversations amongst those of us vested in the arduous process of "progress" moving forward.
#Highway improvement, #street & #road maintenance & #bridge building commonly take center stage.
Mass #transit, #airport & #airways, #municipal #WaterSupply, #waste management along with waste #Water #management,
#power generation & #transmission, #HazardousWaste removal & #storage ALL must be considered while addressing basic underlying societal frameworks. #sustainability
Read 7 tweets

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