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A new job, a #pig, a pregnancy, a move, a pandemic, 5(6) rev and many #pampers later, I’m delighted to share my co-first authorship with @KellerValsecchi in the @AsifaAkhtar1 lab today in @nature. Thread below for summary nature.com/articles/s4158…
In this crazy journey we reconstituted the minimal #Drosophila requirements to achieve #Xchromosome targeting
We systematically asked the hierarchical interdependencies of the known MSL complex members to understand the contribution of #DNAmotif, #interaction_partners and #evolutionary determinants in the process of targeting the single male #Xchromosome for transcriptional upregulation
