Discover and read the best of Twitter Threads about #aldosterone

Most recents (5)

1) Welcome to our new #accredited #tweetorial on #mechanismofaction & impact of meds commonly used in patients with or at risk for #DKD progression: #MRAs, #GLP-1 receptor agonists & #DPP-4 inhibitors. I am Sophia Ambruso DO, @sophia_kidney, from @CU_Kidney. Image
2) This #accredited #tweetorial series on #kidneydisease #DKD through the lens of #T2D is supported by an independent educational grant from the Boehringer Ingelheim/Lilly Alliance and is intended for healthcare providers.
3) This activity is accredited for #physicians #physicianassociates #nurses #NPs #pharmacists. Past programs still eligible for credit can be found at Faculty disclosures are at FOLLOW US for regular programs by expert faculty!
Read 62 tweets
Don’t miss a new accredited #tweetorial launching TOMORROW here on @cardiomet_ce. #Emergencymedicine researcher and devotee of deep understanding of drug mechanism of action @md_pollack will be considering why being #nonsteroidal means better #MRA. Don't miss it! @GoggleDocs
1) Welcome to a #tweetorial where we’ll explore the mechanism of action of mineralocorticoid receptor antagonists (#MRA) & consider why it's so #vogue to be #nonsteroidal. This program is accredited for 0.50 credits for #physicians #nurses #pharmacists. I am @md_pollack. #FOAMed
Read 51 tweets
Thank you to @AJPRenal, to Drs. Zachary Gray (superstar) @StanfordMedRes , Wanzhu Tu, @gchertow, and for ongoing dialogue Dr. Howard Pratt for the opportunity to articulate this concept. 1/13
Many investigators have referenced aldosterone sensitivity. Dr. Wanzhu Tu first employed the term with Dr. Howard Pratt and with the incomparable Dr. John Funder in 2014. @HyperAHA 2/13
Training with Dr. David Pearce @UCSFNephrology , we studied aldosterone-mediated ion transport, but seeing patients with a phenotype of low-renin resistant hypertension- with a normal, but non-suppressed #aldosterone , I started thinking about this more. 3/13
Read 13 tweets
Our #residents got to learn about #syncope & #adrenalinsufficiency today from Rising Chief @LizzyHastie, Chief @photon_ick, & Endo-enthusiast @tsantoscavaiola!!

Check out some highlights below we wanted to make sure we shared with our #MedEd peeps on #MedTwitter!! Image
Don’t forget about adrenal insufficiency!! For patients with things like #syncope or #hypotension, it’s easy to forget about cortisol as a cause! While things like dehydration, infection, & other things may be more common overall… AI is #treatable, so make sure you catch it!!
Primary AI = #adrenal glands themselves are the problem. This means #cortisol AND #aldosterone will be low, while #ACTH AND #Renin will be very elevated in attempt to remedy this! Image
Read 5 tweets
Time for my first #medtwitter #Tweetorial on Insulin and Potassium regulation!

This is part 1 of a tweetorial series on K homeostasis/Hyperkalemia. This is a big topic, so I’ll stick to concepts.

Poll: What percent of total body Potassium is within extracellular fluid?
The answer is only 2%!

That means shifts of even small amounts of K either in or out of the ECF leads to huge changes in plasma K concentration.

A great way to think of K regulation is external and internal K balance.

This interplay was described in a 1978 NEJM review
External Balance revolves around Total Body Potassium (TBK) and is determined by K intake - K excretion.

Internal Balance revolves around the distribution of K w/in our intra- and extracellular fluid compartments

K excretion is primarily through kaliuresis, unless ⬆️diarrhea
Read 8 tweets

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