Discover and read the best of Twitter Threads about #allohsct

Most recents (1)

At @ASH_hematology #ASH22 highlights I am being told some transplanters are refusing to do #AlloHSCT for otherwise eligible #AMLSm younger pts in CR because of bialleic #TP53 +MRD, I don’t think this is acceptable. Counsel on poor outcomes but there is a tail at end of OS curve
Even if it 10%. I anecdotally had few pts who lived for years post transplant going in with TP53 bialleic complex type & MRD+ CR. I don’t think you should deprive pt only possibly of cure just to try to eradicate pre-allo MRD which often does not occur with any pre-transplant tx
Give MAC & throw in early maintenance & hope GVL effect kicks in before relapse. We have to be humble about how we council using data. Encourage trials of novel agents, counsel patients honestly, if older pt who can’t get MAC then maybe discourage transplant not in younger pt
Read 4 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!